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Cialis (Tadalafil)
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Cialis is a highly effective, long-acting prescription medication containing the active ingredient Tadalafil, primarily used to treat erectile dysfunction (ED)and symptoms of benign prostatic hyperplasia by improving blood flow to the penis for up to 36 hours.
- Extended 36-hour duration
- Spontaneity with "daily" options
- Works with or without food
- Discreet UK home delivery
More information
Cialis, known medically as Tadalafil, is our most frequently recommended treatment for men seeking a reliable solution for erectile dysfunction because its long window of efficacy offers significantly more spontaneity than traditional alternatives. It is typically prescribed for adult men experiencing persistent difficulty in achieving or maintaining an erection, as well as those managing the urinary symptoms associated with an enlarged prostate.
— Rachael Clarke MRCPharm MFRPSI FRSPH (GPHC Number: 2061366)
You can buy Cialis online safely through Mail My Meds by completing a convenient online consultation with a UK-registered prescriber. Once your assessment is approved, your medication is dispensed from our pharmacy (GPHC Number: 9011560) and shipped via discreet home delivery in plain packaging to ensure your privacy at every stage.
The tadalafil price varies depending on the strength and pack size you require. Branded Cialis is available at a premium, and our pricing is transparent with no hidden prescription fees included in the final checkout price.
Mail My Meds provides several delivery options to suit your schedule, including Royal Mail Tracked 24 and guaranteed next-day delivery for orders approved before our afternoon cutoff. All treatments are sent in robust, non-branded packaging so that the contents remain entirely confidential from the moment they leave our pharmacy.
Cialis is a clinically proven medication used to treat erectile dysfunction (ED) and the signs of benign prostatic hyperplasia (BPH) in men. Unlike some other treatments, Cialis provides a flexible window of effect, allowing you to achieve an erection at any point of sexual arousal within a 36-hour period after taking a single dose.
The active ingredient in Cialis is Tadalafil, a potent chemical compound that belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. Tadalafil works specifically by relaxing the smooth muscles in the blood vessels of the penis, which increases blood flow and enables a firm erection when combined with sexual stimulation.
Most user experiences with Cialis are positive, with clinical data from NICE and the NHS indicating that approximately 80% of men find the treatment effective for improving their sexual performance. Patients often refer to it as "the weekend pill" because of its long-lasting nature, noting that it reduces the pressure to "time" their medication perfectly before intimacy.
The Patient Information Leaflet (PIL) is included in every box of Cialis we dispense and contains vital safety data regarding your treatment. We strongly recommend reading the PIL before your first dose to understand the full list of ingredients, specific contraindications, and storage instructions.
Cialis works by inhibiting the PDE5 enzyme, which is responsible for the breakdown of cyclic GMP, a substance that promotes muscle relaxation and blood flow in the penis. By maintaining higher levels of cyclic GMP, Tadalafil ensures that the blood vessels remain dilated during sexual arousal, making it easier to maintain an erection sufficient for sexual activity.
To use Cialis effectively, you should swallow one tablet whole with water at least 30 to 60 minutes before you anticipate sexual activity. It can be taken with or without food, though avoiding excessively heavy or high-fat meals may help the medication absorb more quickly into your bloodstream.
The standard Cialis dosage for on-demand use is 10mg or 20mg, while Cialis Daily is available in 2.5mg or 5mg strengths for those who want to be ready at any time. Your prescriber will recommend the most appropriate strength based on your medical history and the frequency of your symptoms.
| Type | Strength | Frequency |
|---|---|---|
| On-Demand | 10mg / 20mg | As needed (once per 24-36 hrs) |
| Daily Use | 2.5mg / 5mg | Once every day |
Common side effects of Cialis include headaches, indigestion, back pain, muscle aches, and facial flushing. While most of these are mild and dissipate as the medication leaves your system, you should seek immediate medical attention if you experience chest pain, sudden vision loss, or a prolonged erection lasting more than four hours (priapism).
You must not take Cialis if you are currently using nitrate medications for chest pain, as this can cause a dangerous drop in blood pressure. Men with severe heart conditions, recent history of stroke, or those with certain eye conditions like retinitis pigmentosa should consult their GP before attempting to order Cialis online.
Cialis provides a much longer duration of action (36 hours) compared to Viagra (Sildenafil), which typically lasts for 4 to 6 hours. While Viagra is often affected by food intake, Cialis remains effective regardless of whether you have eaten, making it a more versatile choice for many patients.
Can you buy Cialis over the counter in the UK?
No, high-strength Cialis (10mg and 20mg) requires a Cialis prescription from a qualified healthcare professional, although lower-strength "Cialis Together" may be available after a pharmacist consultation. At Mail My Meds, we provide the necessary clinical assessment online so you can access the appropriate strength legally and safely.
How long does Cialis take to work?
Cialis typically begins to work within 30 minutes, though it can take up to 2 hours to reach peak concentration in the blood. For the best experience, we recommend taking the tablet at least one hour before sexual activity.
Can I drink alcohol while taking Tadalafil?
While a small amount of alcohol is generally safe, excessive drinking can increase the risk of side effects like dizziness and may make it more difficult to achieve an erection, potentially counteracting the benefits of the medication.
The information provided on this page is for general informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or another qualified health provider with any questions you may have regarding a medical condition.
This clinical content is regularly reviewed by our team of medical experts and UK-registered pharmacists to ensure it remains up-to-date, accurate, and aligned with current BNF and NICE guidelines.

