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Clobetasol Ointment
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Clobetasol Ointment is a very high-potency topical steroid containing the active ingredient clobetasol propionate, specifically formulated to reduce the redness, swelling, and itching associated with severe inflammatory skin conditions like psoriasis and recalcitrant eczema.
- Very potent topical corticosteroid for severe skin inflammation
- Effective relief for flare-ups of psoriasis and resistant eczema
- Ointment formulation provides intensive hydration for dry skin
- Convenient online clinical review and tracked UK delivery
More information
"Clobetasol Ointment is typically prescribed as a short-term intervention for adults with severe inflammatory dermatoses, such as plaque psoriasis, lichen planus, and discoid lupus erythematosus, which have not responded sufficiently to milder corticosteroids. As a super-potent treatment, it is essential to follow the directed pulse-therapy or short-course application to manage flare-ups effectively while minimising the risk of systemic absorption." - Rachael Clarke MRCPharm MFRPSI FRSPH (GPHC Number: 2061366)
You can buy Clobetasol Ointment safely through Mail My Meds by completing a brief online consultation that is reviewed by a UK registered prescriber to ensure the treatment is suitable for your skin condition. Once approved, your prescription is fulfilled and shipped directly from our registered pharmacy (GPHC Number: 9011560) in discreet packaging to maintain your privacy.
The cost of Clobetasol Ointment at Mail My Meds reflects the clinical service provided, including the professional consultation and the medication itself. We aim to provide a competitive and transparent pricing structure for both private and NHS prescription services without hidden fees.
We provide a range of reliable delivery services across the UK to ensure you receive your medication promptly. All orders are sent via tracked methods, allowing you to monitor your treatment from our pharmacy to your doorstep.
Clobetasol Ointment is a super-potent topical medicine used to treat severe skin conditions characterised by intense inflammation and itching. It is most commonly used for psoriasis and eczema that have proven resistant to other treatments, helping to clear patches of thickened or scaly skin.
The active ingredient is clobetasol propionate at a concentration of 0.05% w/w. This compound is a synthetic corticosteroid that possesses high glucocorticoid activity, making it one of the most powerful topical anti-inflammatory agents available.
Many patients report a rapid reduction in skin redness and irritation within a few days of starting treatment. Because it is a greasy ointment, users often find it particularly beneficial for very dry, scaly areas of skin where a cream might absorb too quickly without providing enough of a moisture barrier.
Every pack of Clobetasol Ointment includes a Patient Information Leaflet (PIL) which contains essential details regarding its use and safety. We strongly recommend reading the PIL thoroughly before your first application to understand the specific instructions for your medication.
Clobetasol Ointment works by suppressing the body's immune response in the local area of application, which prevents the release of chemicals that cause inflammation. By narrowing the blood vessels and reducing the activity of the immune system, it effectively calms the swelling and irritation of the skin.
You should apply a thin layer of the ointment to the affected area once or twice daily as directed by your healthcare professional. Wash your hands before and after application, and ensure the skin is clean and dry before applying the medication.
The standard dosage involves applying a small amount of ointment, often measured in Fingertip Units (FTU), to cover the affected area. Treatment is usually limited to a maximum of four weeks to prevent the risk of side effects associated with long-term steroid use.
While most people tolerate the medication well, some may experience local side effects at the site of application. Common and rare side effects are summarised in the table below:
| Frequency | Potential Side Effects |
|---|---|
| Common | Burning, stinging, or itching at the application site. |
| Uncommon | Skin thinning (atrophy), stretch marks, or visible blood vessels. |
| Rare | Adrenal suppression or allergic contact dermatitis. |
Do not use Clobetasol Ointment on your face, groin, or underarms unless specifically instructed by a doctor. Avoid using the ointment on broken, infected, or thin skin, and do not cover the treated area with airtight dressings (occlusion) unless advised, as this increases the risk of systemic absorption.
Clobetasol is classified as "very potent," sitting at the top of the steroid ladder, whereas medications like hydrocortisone are "mild." In the UK, approximately 1 in 10 adults suffer from eczema, and many require a step-up approach where they move from moderate steroids like clobetasone to very potent ones like clobetasol during a severe flare.
Can I use Clobetasol Ointment on my face?
You should generally avoid using this very potent steroid on the face because the skin there is thinner and more prone to permanent damage or side effects like perioral dermatitis.
How long can I use Clobetasol Ointment for?
Treatment is typically restricted to a maximum of 2 to 4 weeks at a time to ensure safety and prevent the skin from thinning.
Is Clobetasol Ointment available over the counter?
No, because of its high potency, Clobetasol Ointment is a prescription-only medication (POM) in the UK and requires a consultation with a registered prescriber.
The information provided on this page is for general informational purposes only and should not replace seeking advice from a medical professional for personalised treatment. Always consult with a doctor or pharmacist to ensure that Clobetasol Ointment is appropriate for your specific health needs.
Our content is regularly reviewed by our team of medical experts to ensure it remains up to date, accurate, and aligned with current clinical guidelines in the UK. We prioritise providing reliable health information to support our patients' well-being.

