Free delivery on all NHS prescriptions — order now
Combodart
Images for illustrative purposes only
Combodart is a prescription medication used to treat men with an enlarged prostate, known as Benign Prostatic Hyperplasia (BPH), by combining the active ingredients dutasteride and tamsulosin to improve urinary flow and reduce the risk of surgery.
- Dual-action formula for managing Benign Prostatic Hyperplasia (BPH) symptoms
- Combines an alpha-blocker with a 5-alpha reductase inhibitor for effective relief
- Convenient daily capsule for long-term prostate health management
- Available via our secure online consultation or with a valid NHS prescription
More information
"Combodart is a highly effective dual-therapy treatment typically prescribed for men suffering from moderate to severe symptoms of Benign Prostatic Hyperplasia (BPH). By combining two distinct mechanisms of action, it helps to both shrink the prostate gland and relax the muscles within the bladder neck, making it significantly easier to pass urine and reducing the long-term risk of acute urinary retention." - Rachael Clarke MRCPharm MFRPSI FRSPH (GPHC Number: 2061366)
You can buy Combodart online through Mail My Meds by completing a straightforward online consultation with a registered prescriber. Once your assessment is reviewed and approved, your medication is shipped directly from our pharmacy (GPHC Number: 9011560) in discreet packaging to ensure your privacy. We also fulfil traditional NHS and private prescriptions for patients who have already been diagnosed and prescribed this treatment by their GP.
The cost of Combodart will depend on whether you are fulfilling a standard NHS prescription or opting for a private prescription through our online clinic. While NHS prescriptions carry a flat-rate charge (unless you are exempt), private prescription pricing reflects the convenience of the clinical service and the medication itself. You can view the current price for your required quantity at the top of this page.
We offer a range of reliable delivery options to suit your schedule, ensuring your prostate treatment arrives quickly and securely. All orders are sent in plain, non-branded packaging to maintain confidentiality. You will receive tracking information once your order has been dispatched from our UK-based pharmacy.
Combodart is a combination medication specifically formulated to manage the symptoms and progression of Benign Prostatic Hyperplasia (BPH), a non-cancerous enlargement of the prostate gland. This condition is common in men as they age and can lead to lower urinary tract symptoms (LUTS) such as a weak urine stream, frequent nighttime urination, and the feeling that the bladder has not fully emptied. This medication is usually recommended when single-agent treatments have not provided sufficient relief.
Each Combodart capsule contains two primary active ingredients that work together to manage BPH symptoms.
- Dutasteride (0.5mg): A 5-alpha reductase inhibitor that lowers levels of dihydrotestosterone (DHT), the hormone responsible for prostate growth.
- Tamsulosin Hydrochloride (0.4mg): An alpha-blocker that relaxes the smooth muscle in the prostate and urethra.
Many patients report a significant improvement in their quality of life and urinary flow within a few weeks to months of starting treatment. While tamsulosin often provides rapid relief by relaxing muscles, the dutasteride component may take several months to achieve its full effect in shrinking the prostate gland. Most users find the once-daily dosing regimen easy to maintain for long-term management.
It is essential to read the Patient Information Leaflet (PIL) provided with your medication before you start treatment. This document contains vital information regarding ingredients, usage instructions, and safety data. You can access the electronic version of the leaflet via the MHRA or EMC websites to stay updated on the latest clinical guidelines for this medication.
The treatment works by targeting two different physiological causes of urinary obstruction associated with an enlarged prostate. Tamsulosin acts as a "functional" treatment, quickly relaxing the muscles to allow urine to flow more freely through the urethra. Dutasteride acts as a "structural" treatment, gradually reducing the physical size of the prostate over time by blocking the hormones that cause it to grow.
You should take one capsule daily, approximately 30 minutes after the same meal each day. Consistency is key to maintaining stable levels of the medication in your bloodstream. The capsules must be swallowed whole with water and should never be crushed, chewed, or opened, as the contents can irritate the lining of your mouth and throat.
The standard dosage for adult men is one Combodart capsule (0.5mg/0.4mg) taken once per day. Do not increase your dose or take the medication more frequently than directed by your prescriber. If you miss a dose, skip it and return to your regular schedule the following day. Never double up to make up for a missed capsule.
Like all medicines, this treatment can cause side effects, although not everyone experiences them. Common side effects may include:
- Dizziness or lightheadedness, particularly when standing up quickly.
- Changes in sexual function, such as decreased libido or ejaculation disorders.
- Breast tenderness or enlargement (gynaecomastia).
- Occasional skin rashes or itching.
This medication is strictly for use by men and must never be taken by women, children, or adolescents. Pregnant women should avoid handling leaking capsules, as the active ingredient dutasteride can be absorbed through the skin and may harm the development of a male foetus. You should also inform your doctor if you are planning to undergo cataract surgery, as tamsulosin can affect the pupils during the procedure (Floppy Iris Syndrome).
Combodart is often compared to monotherapies or other combination treatments for BPH.
| Treatment | Active Ingredients | Primary Benefit |
|---|---|---|
| Combodart | Dutasteride & Tamsulosin | Dual-action: Shrinks prostate and relaxes muscles. |
| Tamsulosin (Flomaxtra) | Tamsulosin only | Fast relief of urinary flow symptoms only. |
| Finasteride (Proscar) | Finasteride only | Long-term reduction of prostate size only. |
How long does it take for Combodart to work?
While the tamsulosin component may improve urinary flow within days, the dutasteride component can take 3 to 6 months to significantly reduce the size of the prostate gland. It is important to continue taking the medication as prescribed even if you do not notice immediate changes.
Can I drink alcohol while taking this?
It is generally advised to limit alcohol intake while taking tamsulosin, as alcohol can increase the risk of dizziness and low blood pressure, especially when standing up from a sitting position.
Do I need a prescription for Combodart?
Yes, Combodart is a Prescription Only Medicine (POM) in the UK. You can obtain a prescription through our online consultation service if you meet the clinical criteria, or send us your existing NHS or private prescription for dispensing.
The information provided on this page is for general informational purposes only and should not replace seeking professional medical advice from a doctor or pharmacist. Always consult a healthcare professional for personalised guidance regarding your health condition and treatments.
Our content is regularly reviewed by our team of medical experts and registered pharmacists to ensure it remains accurate, up to date, and compliant with UK clinical standards. We prioritise providing reliable information to help you manage your health effectively.

