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- Dermovate Cream (Clobetasol Propionate)
Dermovate Cream (Clobetasol Propionate)
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Dermovate Cream is a high-potency topical corticosteroid containing 0.05% clobetasol propionate, specifically formulated to reduce severe inflammation and pruritus in patients suffering from resistant skin conditions such as psoriasis and chronic eczema.
- Contains clobetasol propionate, the most powerful category of topical steroid
- Fast-acting relief for flare-ups of discoid lupus and lichen planus
- Available via a secure online consultation
- Direct home delivery from a UK-registered GPhC pharmacy
More information
"Dermovate is a highly effective, super-potent steroid typically prescribed to adults and children over one year old for the short-term treatment of severe inflammatory skin diseases like psoriasis and recalcitrant dermatitis that have not responded to milder steroid creams. As a very strong medication, it must be used sparingly and only under the supervision of a healthcare professional to manage specific flare-ups effectively."
- Rachael Clarke MRCPharm MFRPSI FRSPH (GPHC Number: 2061366)
You can buy Dermovate Cream safely through our online pharmacy following a digital consultation with a registered UK prescriber to ensure this potent medication is suitable for your clinical needs. Once approved, your prescription is dispensed and shipped directly from our registered pharmacy (GPHC Number: 9011560) in discreet packaging to ensure your privacy and convenience.
The price for Dermovate 0.05% Cream starts from competitive rates for a 30g tube, offering an affordable solution for those needing private prescriptions for chronic skin management. We aim to provide transparent pricing that reflects the high quality of care and the cost of the professional consultation included in our service.
Mail My Meds provides flexible delivery options including tracked next-day delivery across the UK for all approved Dermovate orders placed before our daily cut-off time. We understand that managing a painful skin flare-up is urgent, so we prioritise efficient logistics to get your clobetasol propionate treatment to your doorstep quickly.
Dermovate Cream is a super-potent topical steroid used primarily to treat severe skin conditions like psoriasis, eczema, and lichen planus by reducing the chemicals in the body that cause inflammation. Unlike milder treatments, this clobetasol propionate 0.05% formulation is reserved for cases where other corticosteroids have failed to provide relief.
The active ingredient in this medication is clobetasol propionate, which is classified by the BNF as a very potent topical corticosteroid. Each gram of the cream contains 0.5mg of clobetasol propionate, alongside excipients like cetostearyl alcohol and chlorocresol which help maintain the cream's consistency and stability.
Most users report a significant reduction in redness, swelling, and itching within a few days of starting Dermovate treatment, particularly those with stubborn plaque psoriasis. Clinical evidence from the National Institute for Health and Care Excellence (NICE) supports its efficacy in rapidly calming severe dermatological inflammation when used as directed.
Every pack of Dermovate includes a Patient Information Leaflet (PIL) which contains essential data on ingredients, application guides, and potential interactions. You should read this leaflet thoroughly before starting treatment. Digital versions are also available via the eMC.
Clobetasol propionate works by entering the skin cells and preventing the release of inflammatory substances like prostaglandins and leukotrienes that cause blood vessels to widen and the skin to become red and itchy. According to the NHS, this ""vasoconstrictive"" action is what makes it so effective at suppressing the immune response in the localised area of application.
Apply a thin layer of Dermovate Cream to the affected area of skin once or twice daily for a maximum of four weeks, ensuring you wash your hands before and after application unless treating the hands. You should use the ""Finger Tip Unit"" (FTU) method to measure the correct amount of cream, as using too much can increase the risk of systemic absorption.
The standard dosage for Dermovate 0.05% is a small amount applied thinly to the affected area. A single 30g tube should typically last for several weeks of short-term treatment. It is recommended that the total dose does not exceed 50g per week to prevent adrenal suppression and other side effects.
Common side effects of clobetasol propionate include a burning or stinging sensation upon application, skin thinning (atrophy), and the appearance of stretch marks if used for prolonged periods. More serious side effects can occur if the medication is absorbed into the bloodstream, which is why it should not be used on large areas of the body or under airtight dressings unless advised by a doctor.
Do not use Dermovate on your face, private parts, or anus unless specifically instructed by your specialist, as the skin in these areas is thinner and more prone to damage. It should never be used on broken skin, infected skin (such as fungal infections, ringworm, or jock itch), or for conditions like acne or rosacea, as steroids can worsen these issues.
| Treatment | Potency Class | Best For |
|---|---|---|
| Dermovate | Very Potent | Severe, resistant psoriasis and eczema. |
| Betnovate | Potent | Moderate to severe eczema and dermatitis. |
| Eumovate | Moderate | Mild eczema and insect bites. |
| Hydrocortisone | Mild | Face rashes and very mild irritation. |
Can I use clobetasol propionate for a yeast infection or fungus?
No, you should not use clobetasol propionate for fungal or yeast infections like ringworm or jock itch because steroids can actually mask the infection and allow it to spread. Antifungal treatments are required for these conditions.
Is Dermovate cream a steroid?
Yes, Dermovate is a ""very potent"" topical steroid, which is the strongest class of corticosteroid available for skin conditions in the UK.
Can you buy Dermovate cream over the counter?
Dermovate is a prescription-only medication (POM) in the UK and cannot be purchased over the counter due to its high strength and the need for medical supervision.
Can I use Dermovate on my face?
You should generally avoid using Dermovate on your face as it can cause permanent skin thinning and may trigger conditions like perioral dermatitis or worsen rosacea.
What happens if you use too much clobetasol propionate?
Using too much clobetasol propionate over a long period can lead to skin thinning, stretch marks, and potential absorption into the blood, which may affect your adrenal glands.
The information provided on this page is for general informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition or the use of Dermovate Cream.
Our clinical content is regularly reviewed by a team of qualified medical experts and pharmacists to ensure it remains accurate, reflects current UK prescribing guidelines (BNF/NICE), and provides the most up-to-date safety information for our patients.

