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Domperidone
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Domperidone is a prescription-only medication primarily used for the short term treatment of nausea and vomiting in adults and adolescents. As a dopamine antagonist, the active ingredient domperidone works by increasing motility in the upper gastrointestinal tract to help move food through the stomach more efficiently.
- Fast-acting relief from symptoms of nausea and vomiting
- Effective dopamine antagonist that aids gastric emptying
- Convenient online consultation with a registered UK prescriber
- Discreet delivery from our UK based registered pharmacy
More information
"Domperidone is specifically indicated for the relief of symptoms related to nausea and vomiting in patients aged 12 years and older who weigh at least 35kg. It is typically prescribed for short durations, usually not exceeding one week, to manage acute sickness and help restore normal gastric function. Patients must ensure they do not have underlying heart conditions before commencing treatment." - Rachael Clarke MRCPharm MFRPSI FRSPH (GPHC Number: 2061366)
You can buy Domperidone through our secure online platform following a successful clinical assessment by one of our registered UK prescribers. The process is straightforward: simply complete a brief online consultation which is then reviewed to ensure the treatment is suitable for your specific health needs. Once approved, your order is dispensed and shipped directly from our pharmacy (GPHC Number: 9011560) in discreet packaging for your privacy.
The price of Domperidone at Mail My Meds is competitive and includes the cost of your online clinical consultation and the private prescription fee. We aim to provide an affordable and transparent pricing structure for patients looking to manage symptoms of sickness without the need for a traditional face-to-face GP appointment.
We offer various reliable delivery methods to ensure you receive your medication promptly after your consultation is approved. Our delivery service is designed to be efficient and discreet, with tracking available so you can monitor the progress of your treatment from our pharmacy to your doorstep.
Domperidone is a medicinal treatment used to stop you from feeling or being sick, a condition known as nausea and vomiting. While it was previously used for broader issues like bloating and heartburn, current UK medical guidance restricts its use to the relief of acute sickness symptoms to ensure patient safety.
The active ingredient in this medication is domperidone, a prokinetic medicine that acts on dopamine receptors. By blocking these receptors in the gut and the part of the brain responsible for the vomiting reflex, it effectively reduces the sensation of nausea.
Many users report that Domperidone is highly effective at reducing the urge to vomit within 30 to 60 minutes of taking a dose. Patients often find it particularly helpful when taken before meals to prevent the discomfort associated with delayed stomach emptying.
The Patient Information Leaflet (PIL) is included with every order and provides essential data on how to store and use your medication safely. You should read this document thoroughly before starting your treatment to understand the full safety profile and ingredient list.
Domperidone works by increasing the movements or contractions of the stomach and bowel, which helps move food more quickly through the digestive system. It also blocks dopamine signals to the "vomiting centre" in the brain, which effectively suppresses the feeling of nausea and prevents vomiting.
You should take this medication exactly as directed by your prescriber, usually 15 to 30 minutes before food for the best results. Taking it after meals can delay the absorption, meaning it may take longer to provide relief from your symptoms.
The standard dosage for adults and adolescents weighing 35kg or more is 10mg taken up to three times daily. You should always use the lowest effective dose for the shortest possible duration, with a maximum daily limit of 30mg.
| Patient Group | Standard Dose | Max Daily Dose |
|---|---|---|
| Adults (12+ years, 35kg+) | 10mg (1 tablet) | 30mg (3 tablets) |
Common side effects of Domperidone are generally mild and may include a dry mouth or feelings of drowsiness. While rare, more serious side effects can involve heart rhythm disturbances, so it is vital to report any palpitations or fainting to a healthcare professional immediately.
- Dry mouth
- Drowsiness or dizziness
- Headache
- Diarrhoea
You must not take Domperidone if you have a history of heart disease, heart rhythm issues, or severe liver impairment. It is also contraindicated if you are taking certain other medications that affect heart rhythm, such as specific antibiotics or antifungal treatments.
Domperidone is often preferred over other anti-emetics like Metoclopramide for certain patients because it does not cross the blood-brain barrier as easily, reducing the risk of neurological side effects. However, unlike some over-the-counter options, it requires a prescription and carries specific cardiac warnings that must be considered by a prescriber.
Can I take Domperidone while pregnant?
Domperidone is generally not recommended during pregnancy unless specifically advised by a specialist who has weighed the benefits against potential risks. If you are pregnant or planning to become pregnant, you should consult your doctor before using this treatment.
How long does it take for Domperidone to work?
Most patients begin to feel the effects of the medication within 30 to 60 minutes of ingestion. To ensure it works as quickly as possible, it is best taken on an empty stomach before your main meals.
Is Domperidone available on the NHS?
Yes, Domperidone is available on the NHS for specific indications, but many patients choose to buy it via a private online pharmacy like Mail My Meds for greater convenience and faster access to a clinical consultation.
The information provided on this page is for general informational purposes only and shouldn't replace seeing a medical professional for personalised advice. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Our content is regularly reviewed by our team of medical experts to ensure it is up to date and accurate. We adhere to strict clinical standards to provide reliable health information to our patients in the UK.

