Elleste Duet

"Elleste Duet is a widely prescribed cyclical HRT treatment designed specifically for women who still have an intact womb and are experiencing symptoms of the menopause or perimenopause. By mimicking the natural hormonal cycle, it effectively manages symptoms like vasomotor instability while providing the necessary progestogen to protect the endometrial lining. It is also an important clinical option for the prevention of osteoporosis in postmenopausal women at high risk of fractures." - Rachael Clarke MRCPharm MFRPSI FRSPH (GPHC Number: 2061366)

You can buy Elleste Duet online through Mail my Meds by completing a convenient online consultation with a registered prescriber. Once your assessment is reviewed and approved, your medication is shipped directly from our pharmacy (GPHC Number: 9011560) in discreet packaging. This process ensures you receive genuine UK-licensed medication following a professional clinical safety check.

The cost of your treatment will depend on whether you are fulfilling an NHS prescription or opting for a private prescription service. While NHS charges are fixed at the standard national rate, private prescription costs include the price of the medication and our clinical delivery service. You can view the final price at the checkout stage after your consultation.

We offer various delivery methods to ensure your HRT reaches you promptly and securely. All orders are sent in neutral, unbranded packaging to maintain your privacy. Once your prescription is approved by our medical team, you will be able to select your preferred shipping speed during the final stages of your order.

Elleste Duet is a hormone replacement therapy (HRT) primarily used to treat symptoms associated with the menopause and to prevent osteoporosis. It is a "sequential" or "cyclical" treatment, meaning it provides a steady dose of oestrogen and a scheduled dose of progestogen. This type of therapy is typically recommended for women who are still having periods or who have had a period within the last 12 months.

The tablets contain two primary active substances that work together to balance hormone levels in the body. These ingredients are estradiol (as estradiol hemihydrate), which is a naturally occurring form of the female sex hormone oestrogen, and norethisterone acetate, a synthetic version of the hormone progesterone.

Many patients report a significant improvement in their quality of life after starting this treatment, particularly regarding the reduction of hot flushes and improved sleep patterns. Statistics suggest that around 80% of women in the UK will experience menopause symptoms, and many find that combined HRT provides the most effective relief. Some users may experience a withdrawal bleed at the end of each pack, similar to a regular period.

It is essential to read the Patient Information Leaflet (PIL) provided with your medication for a comprehensive guide on safety and usage. The PIL contains vital data regarding the chemical composition, storage instructions, and a full list of potential interactions. You should always keep this leaflet for reference throughout your treatment course.

This medication works by supplementing the declining levels of oestrogen in the body during the menopause transition. The estradiol alleviates symptoms like vaginal dryness and mood swings, while the norethisterone acetate ensures the lining of the womb does not thicken excessively, which reduces the risk of endometrial complications.

You should take one tablet every day at approximately the same time, following the arrows and days marked on the foil blister strip. The tablets must be swallowed whole with a glass of water and can be taken with or without food. It is important not to have a break between packs. When you finish one strip, you should start the next one the following day.

The standard dosage involves taking one tablet daily without interruption. Treatment usually begins with the lowest effective dose for the shortest duration necessary to manage your symptoms. Your prescriber will determine whether the 1mg or 2mg strength is most appropriate for your clinical needs.

Like all medicines, this HRT can cause side effects, although not everyone will experience them. Most symptoms are mild and tend to settle within the first few months of treatment as your body adjusts to the hormones.

Before starting HRT, you must inform your prescriber if you have a history of blood clots, liver disease, or oestrogen-sensitive cancers. HRT can slightly increase the risk of certain conditions, such as breast cancer and deep vein thrombosis (DVT). Regular check-ups with your doctor are recommended to monitor your health while taking this medication.

Elleste Duet is a sequential oral tablet, making it distinct from continuous combined treatments like Elleste Duet Conti or transdermal options like Evorel patches. While patches may be preferred for those with a higher risk of blood clots, tablets remain a highly effective and popular choice for many women due to their ease of use and precise dosing.

Can I get Elleste Duet on the NHS?

Yes, we can fulfil your NHS prescriptions for this medication if you have a valid prescription from your GP. You can also purchase it privately through our online consultation service if you do not have a prescription.

What should I do if I miss a dose?

If you forget a tablet and it is less than 12 hours late, take it immediately. If more than 12 hours have passed, skip the missed dose and take the next one at the usual time. Do not take a double dose to make up for a forgotten tablet.

Will I still have a period?

Because this is a sequential HRT, most women will experience a regular "withdrawal bleed" every month toward the end of the blister strip. This is normal and indicates the progestogen is working to protect the womb lining.

The information provided on this page is for general informational purposes only and should not replace seeking advice from a medical professional. Always consult with a doctor or pharmacist for personalised medical guidance regarding your specific health condition and treatment options.

Our content is regularly reviewed by our team of medical experts to ensure it remains up to date, accurate, and aligned with current UK clinical guidelines. We strive to provide reliable information to help you make informed decisions about your healthcare.