Free delivery on all NHS prescriptions — order now
- Home
- Chronic Conditions
- Diabetes
- Gliclazide MR
Gliclazide MR
Images for illustrative purposes only
Gliclazide MR is a modified-release oral medication containing the active ingredient gliclazide, specifically formulated to help adults manage high blood sugar levels associated with type 2 diabetes mellitus.
- Effective blood sugar management for type 2 diabetes
- Modified-release formula for consistent glucose control
- Convenient UK delivery for NHS and private prescriptions
- Online consultation with a registered prescriber included
More information
"Gliclazide MR is a widely utilised sulfonylurea medication prescribed to help control blood glucose levels in patients where diet and exercise alone have not been sufficient. By stimulating the pancreas to produce more insulin, it plays a vital role in a comprehensive diabetes management plan." - Rachael Clarke MRCPharm MFRPSI FRSPH (GPHC Number: 2061366)
You can buy Gliclazide MR safely through the Mail my Meds online pharmacy by completing a straightforward clinical consultation for review by a registered prescriber. Once your request is approved, your medication is dispensed and shipped directly from our registered UK pharmacy (GPHC Number: 9011560) in discreet packaging to ensure your privacy.
The price of Gliclazide MR at Mail my Meds is competitive and includes the cost of your online clinical assessment and carbon-neutral delivery options. We provide transparent pricing for both private prescriptions and the standard NHS prescription charge for eligible patients, ensuring you receive affordable care without hidden fees.
Mail my Meds offers reliable and fast delivery services across the UK to ensure your diabetes treatment arrives when you need it. We provide tracked shipping methods so you can monitor your order from our pharmacy to your doorstep, with options for expedited delivery available during the checkout process.
Gliclazide MR is a prescription-only medicine used to treat type 2 diabetes, a condition where the body does not produce enough insulin or cannot use the insulin it makes effectively. This modified-release version of the drug allows the active ingredient to enter your system gradually over 24 hours, helping to maintain stable blood sugar levels throughout the day and night.
The sole active ingredient in this medication is gliclazide, which belongs to a group of medicines known as sulfonylureas. Each modified-release tablet is engineered with a special matrix that controls the release of the drug, often reducing the frequency of dosing compared to standard-release versions.
Many users report that Gliclazide MR is a convenient treatment option because it typically only requires a single daily dose taken with breakfast. Patients often find it effective at lowering their HbA1c levels, though some experience mild initial side effects as their body adjusts to the improved glucose regulation.
The Patient Information Leaflet (PIL) is included in every box of medication and provides essential details on usage, safety and ingredients. You should read this document thoroughly before starting your treatment, and you can also access a digital version through our website or the electronic Medicines Compendium (eMC).
Gliclazide MR works by increasing the amount of insulin produced by your pancreas, which helps move sugar from your blood into your cells for energy. By binding to specific receptors on the beta cells in the pancreas, it triggers a controlled release of insulin that mimics the body's natural response to food intake.
You should take Gliclazide MR exactly as directed by your healthcare provider, usually as a single dose taken at breakfast time. It is vital to swallow the tablets whole with a glass of water and never crush or chew them, as this would destroy the modified-release mechanism and release the medication too quickly.
The dosage of Gliclazide MR is individualised based on your blood sugar response and ranges typically from 30mg to 120mg per day. Most patients start on a lower dose which may be gradually increased by a clinician until your glucose levels are effectively stabilised.
While many people use Gliclazide MR without significant issues, some individuals may experience side effects ranging from mild to more serious. The most common risk associated with sulfonylureas is low blood sugar, also known as hypoglycaemia.
| Common Side Effects | Occasional Side Effects |
|---|---|
| Hypoglycaemia (low blood sugar) | Indigestion or stomach ache |
| Nausea | Skin rash or itching |
| Dizziness | Changes in vision (temporary) |
Before taking Gliclazide MR, you must inform your prescriber if you have kidney or liver problems, or if you have a condition called G6PD deficiency. This medication may not be suitable for individuals with type 1 diabetes or those experiencing diabetic ketoacidosis, and you should always carry a source of sugar in case of hypoglycaemic episodes.
Gliclazide MR is often prescribed as a second-line treatment if Metformin is not suitable or is insufficient on its own. Unlike Metformin, which improves insulin sensitivity, Gliclazide actively increases insulin production, making it a potent tool for glucose control, though it carries a higher risk of weight gain and low blood sugar.
Can I drink alcohol while taking Gliclazide MR?
It is best to limit alcohol consumption because it can increase the risk of hypoglycaemia and may mask the warning signs of low blood sugar. If you do choose to drink, ensure you do so in moderation and always alongside food.
What should I do if I miss a dose?
If you miss a dose of Gliclazide MR, skip the missed dose and take your next dose at the usual time the following morning. Do not take a double dose to make up for a forgotten tablet, as this significantly increases the risk of your blood sugar dropping too low.
Is Gliclazide MR the same as standard Gliclazide?
No, the MR version is a modified-release tablet designed to release the medication slowly over a day, whereas standard tablets release the medication immediately. This usually means the MR version is taken only once a day, whereas standard tablets may be taken multiple times.
The information provided on this page is for general informational purposes only and should not replace seeking advice from a medical professional for personalised care. Always consult with your doctor or a qualified healthcare provider regarding any questions you have about a medical condition or treatment plan.
Our content is regularly reviewed by our team of medical experts to ensure it remains up to date, accurate and reflective of the latest clinical guidelines. We prioritise providing reliable health information to help you make informed decisions about your well-being.

