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Glucophage SR
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Glucophage SR is a prolonged-release medication containing the active ingredient metformin hydrochloride, specifically formulated to manage blood sugar levels in patients with Type 2 diabetes mellitus while being gentler on the digestive system.
- Helps maintain stable blood glucose levels in adults with Type 2 diabetes
- Prolonged-release formula designed to reduce common gastrointestinal side effects
- Slowly releases the active ingredient to simplify your daily medication routine
- Suitable for both new private prescriptions and repeat NHS prescriptions
More information
"Glucophage SR is a foundational treatment for Type 2 diabetes mellitus, particularly effective for patients who require stable glucose management but may struggle with the digestive impact of standard metformin. By releasing the medication slowly throughout the day, it helps control hyperglycaemia with a significantly lower risk of the nausea or discomfort often associated with immediate-release versions."
- Rachael Clarke MRCPharm MFRPSI FRSPH (GPHC Number: 2061366)
You can purchase Glucophage SR through our secure online platform by completing a brief consultation that is reviewed by a registered prescriber. Once your clinical assessment is approved, your medication is dispensed and shipped from our pharmacy (GPHC Number: 9011560) via a discreet home delivery service to ensure your privacy and convenience.
The price of Glucophage SR varies depending on whether you are fulfilling a private prescription or an NHS repeat order. For NHS patients, standard prescription charges apply unless you are exempt, while private patients will see the total cost reflected at the checkout after the consultation process is completed.
We provide several reliable delivery methods to ensure your treatment reaches you safely and promptly across the UK. You can select your preferred shipping speed during the checkout process, and all orders are packaged in plain, unbranded materials to maintain total discretion.
Glucophage SR is a branded, slow-release version of metformin used to treat Type 2 diabetes, a condition where the body does not produce enough insulin or cannot use it effectively. This sustained-release (SR) formulation is often prescribed when diet and exercise alone are insufficient to maintain healthy blood sugar levels, or for patients who experience stomach upset with standard tablets.
The active ingredient in this medication is metformin hydrochloride. Each tablet is engineered with a special coating that controls the rate at which the metformin enters your system, ensuring a steady therapeutic effect over a 24-hour period.
Many patients report that switching to the SR version of metformin significantly improves their daily comfort by reducing instances of bloating and diarrhoea. While individual experiences vary, the transition from immediate-release to prolonged-release is widely regarded as a positive step for long-term treatment adherence.
Every order of Glucophage SR includes a comprehensive Patient Information Leaflet (PIL) that details specific instructions, storage requirements, and safety data. It is essential to read this leaflet thoroughly before starting your treatment to ensure you understand how to manage your medication safely.
Glucophage SR works by improving how your body handles insulin while reducing the amount of sugar produced by your liver. It increases the sensitivity of your muscle cells to insulin and slows down the absorption of glucose from your intestines during digestion.
You should always take Glucophage SR exactly as directed by your healthcare provider, usually once daily with your evening meal. Taking the tablet with food is crucial as it further reduces the risk of digestive side effects and aids in the absorption of the medication.
The appropriate dosage for Glucophage SR is determined by your prescriber based on your latest HbA1c results and your tolerance to the medication. Most adults begin with a lower dose that may be gradually increased to a maximum of 2,000mg per day, depending on clinical need.
While Glucophage SR is generally well-tolerated, some users may experience mild side effects as their body adjusts to the treatment. Common effects include a metallic taste in the mouth, mild nausea, or changes in bowel habits, though these typically resolve quickly.
Before taking Glucophage SR, you must inform your prescriber if you have any history of kidney or liver problems, as these can affect how the drug is cleared from your body. It is also important to discuss your alcohol consumption, as heavy drinking while on metformin can increase the risk of rare but serious complications like lactic acidosis.
| Feature | Glucophage SR | Standard Metformin |
|---|---|---|
| Release Rate | Slow/Sustained | Immediate |
| Dosing Frequency | Typically once daily | Usually 2-3 times daily |
| GI Side Effects | Lower risk | Higher risk |
Can I drink alcohol with Glucophage SR?
It is best to avoid excessive alcohol consumption while taking this medication as it can significantly increase the risk of lactic acidosis and may interfere with your blood sugar control.
Can I take this if I am pregnant?
You should consult your doctor or specialist before using Glucophage SR if you are pregnant or breastfeeding, as they may recommend alternative ways to manage your blood glucose levels.
What should I do if I miss a dose?
If you miss a dose, take it with your next meal unless it is nearly time for your next scheduled dose. Never take a double dose to make up for a forgotten one.
The information provided on this page is for general informational purposes only and should not replace seeking professional medical advice from a qualified healthcare professional. Always consult with your doctor or pharmacist for personalised guidance regarding your specific health condition and treatment plan.
Our content is regularly reviewed by our team of medical experts to ensure it remains up to date, accurate, and aligned with the latest UK clinical guidelines. We are dedicated to providing reliable information to help you manage your health with confidence.

