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Imigran
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Imigran is a clinically proven branded treatment used to alleviate the symptoms of acute migraine attacks and cluster headaches by utilising the active ingredient sumatriptan to narrow widened blood vessels in the brain.
- Fast-acting relief for acute migraine symptoms
- Contains the active ingredient sumatriptan
- Convenient online prescriber consultation
- Discreet UK home delivery on approved orders
More information
"Imigran is a reliable triptan medication typically prescribed for the acute relief of migraine headaches, with or without aura, and can also be used for cluster headaches. It is designed to be taken at the first sign of an attack to effectively reduce vascular swelling and associated symptoms like light sensitivity." - Rachael Clarke MRCPharm MFRPSI FRSPH (GPHC Number: 2061366)
You can buy Imigran safely through Mail My Meds by completing a straightforward online consultation that is reviewed by a UK registered prescriber. If your consultation is approved, your medication is dispensed and shipped directly from our registered pharmacy (GPHC Number: 9011560) in discreet packaging to ensure your privacy. This process removes the need for face-to-face appointments while maintaining high clinical standards for patient safety.
The price of Imigran at Mail My Meds reflects the branded nature of the medication and includes the cost of your online clinical assessment and prescription. While branded treatments often carry a higher price point than generic alternatives, many patients prefer Imigran for its established reputation and manufacturing consistency. You can view current pricing and availability by starting your consultation on our platform.
Mail My Meds provides several delivery options to ensure you receive your migraine treatment quickly and securely across the UK. Once our clinical team approves your order, we utilise tracked delivery services to keep you updated on your package's progress. All orders are sent in plain, unbranded packaging so that the contents remain confidential at all times.
Imigran is a branded prescription medication specifically developed for the acute treatment of migraine attacks and, in certain formulations, cluster headaches. Unlike standard over-the-counter painkillers, Imigran belongs to a class of drugs known as triptans (5-HT1 receptor agonists) which target the specific physiological changes that occur during a migraine. It is used to stop an attack once it has started rather than preventing one from occurring.
The active ingredient in Imigran is sumatriptan, which is present in the form of sumatriptan succinate. This compound acts as a selective agonist for serotonin (5-HT1) receptors located in the cranial blood vessels. By stimulating these receptors, sumatriptan helps to reverse the temporary widening of blood vessels that is thought to be a primary cause of migraine pain and associated symptoms.
Many users report that Imigran provides significant relief within 30 to 60 minutes of ingestion, particularly when taken early in the migraine phase. While individual responses vary, patients often find it more effective than standard analgesics for debilitating symptoms like nausea and light sensitivity. Some users may experience a temporary "triptan sensation" such as heaviness or tingling, but these usually pass quickly as the migraine subsides.
You should always read the Patient Information Leaflet (PIL) provided with your medication for a full list of ingredients, side effects and instructions. The PIL contains essential safety data and specific guidance on how to store and use your treatment correctly. You can access the official electronic medicines compendium (emc) for the Imigran 50mg Tablets Leaflet or the 100mg version depending on your prescription.
Imigran works by mimicking the action of serotonin in the brain to narrow the blood vessels that have dilated during a migraine attack. This vasoconstriction reduces the pressure in the head and inhibits the release of certain natural substances that trigger pain signals and inflammation. By addressing the root vascular cause of the headache, it also helps alleviate secondary symptoms like vomiting and sound sensitivity.
To use Imigran effectively, you should take one dose as soon as you feel the headache phase of a migraine starting. It is not designed to be taken during the "aura" phase (visual disturbances) or as a preventative measure. The tablets should be swallowed whole with water and not crushed or chewed, as this can affect how the medication is absorbed into your system.
The standard dosage for adults aged 18 to 65 is typically one 50mg or 100mg tablet per attack, as determined by your prescriber. If your symptoms improve but then return, you may take a second dose at least 2 hours after the first, provided you do not exceed the maximum daily limit.
| Dose Frequency | Requirement |
|---|---|
| Maximum in 24 hours | 300mg |
| Minimum gap between doses | 2 Hours |
| If first dose fails | Do not take a second for same attack |
Like all medicines, Imigran can cause side effects, although not everybody gets them and they are often short-lived. Common side effects include feelings of heaviness, pressure, or tightness in various parts of the body, including the chest and throat. Other reported effects include:
- Dizziness or drowsiness
- Feeling sick (nausea) or being sick (vomiting)
- Temporary increase in blood pressure
- Shortness of breath
- Aching muscles
Imigran is not suitable for everyone, particularly those with a history of heart disease, stroke, or uncontrolled high blood pressure. You must inform your prescriber if you have liver or kidney problems, or if you are allergic to sulfonamides. It should not be used at the same time as other triptans or ergotamine-containing medications, as this can increase the risk of serious side effects.
Imigran (sumatriptan) is often considered the "gold standard" of triptans because it has the most extensive clinical evidence supporting its use. Compared to other triptans like Zolmitriptan or Rizatriptan, it may have a different speed of onset or side effect profile. While some newer "Gepants" (like Vydura) work by blocking CGRP proteins, Imigran remains a primary choice for many due to its proven efficacy in narrowing blood vessels directly.
Can I take Imigran with paracetamol?
Yes, if the first dose of Imigran does not work for your migraine, you can use standard painkillers like paracetamol or ibuprofen to manage the pain of that specific attack. However, you should not take a second Imigran tablet if the first had no effect.
Is Imigran available on the NHS?
Imigran and its generic version, sumatriptan, are available on NHS prescription. Mail My Meds offers a private online service for those who prefer the convenience of an online consultation and home delivery without visiting a GP surgery.
How quickly does Imigran work?
The tablets usually begin to work within 30 to 60 minutes. Factors such as whether you have eaten or how far into the migraine attack you are can influence the speed of relief.
The information provided on this page is for general informational purposes only and should not replace seeking advice from a medical professional. Always consult with a doctor or pharmacist to ensure that a specific treatment is suitable for your individual health needs and medical history.
Our content is regularly reviewed by our team of medical experts to ensure it is up to date and accurate. We strive to provide reliable information that aligns with current UK clinical guidelines and MHRA standards to help you make informed decisions about your health.

