Free delivery on all NHS prescriptions — order now
Janumet
Images for illustrative purposes only
Janumet is a combination prescription medication used to improve glycaemic control in adults with type 2 diabetes by utilising the active ingredients sitagliptin and metformin hydrochloride.
- Combines sitagliptin and metformin to manage blood sugar effectively
- Reduces the number of daily tablets by merging two medications into one
- Typically does not cause the weight gain associated with some other diabetes treatments
- Dispensed by a registered UK pharmacy following a clinical consultation
More information
"Janumet is typically prescribed for adults with type 2 diabetes when metformin alone does not provide sufficient blood sugar control or for those already successfully using sitagliptin and metformin as separate tablets. It works by helping your body produce more insulin and reducing the amount of sugar made by your liver, making it a robust option for long term glycaemic management." - Rachael Clarke MRCPharm MFRPSI FRSPH (GPHC Number: 2061366)
You can buy Janumet safely through Mail My Meds by completing a brief online consultation that is reviewed by a registered prescriber to ensure the treatment is suitable for you. Once approved, your prescription is fulfilled and shipped from our UK-based pharmacy (GPHC Number: 9011560) using discreet, tracked delivery to your chosen address.
The price of Janumet depends on the strength and quantity required for your specific treatment plan as determined during your consultation. While private prescription costs can vary, we aim to provide competitive pricing for all patients seeking to manage their type 2 diabetes through our online platform.
We offer various delivery methods to ensure you receive your medication promptly and securely after your clinical assessment is successful. All orders are sent in plain packaging to maintain your privacy throughout the transit process.
Janumet is an oral prescription medicine used to treat type 2 diabetes mellitus by helping to lower blood glucose levels in conjunction with diet and exercise. It is specifically designed for patients who require more than one medication to keep their sugar levels within a healthy range, preventing long term complications associated with hyperglycaemia.
The active ingredients in Janumet are sitagliptin (a DPP-4 inhibitor) and metformin hydrochloride (a biguanide). These two components work through different mechanisms to provide a comprehensive approach to managing blood sugar levels throughout the day and night.
Janumet works by increasing insulin production after meals and reducing the amount of glucose produced by the liver. Sitagliptin prevents the breakdown of incretin hormones which signal the pancreas to release insulin, while metformin improves insulin sensitivity and slows the absorption of sugar in the digestive tract.
You should take Janumet exactly as your prescriber has directed, typically twice daily with a meal. Taking the tablet with food is essential as it helps to reduce the likelihood of experiencing an upset stomach, which is a common side effect associated with the metformin component.
The standard dosage of Janumet is usually one tablet taken twice a day, though the specific strength of sitagliptin and metformin will be tailored to your individual needs. Your prescriber will determine the correct dose based on your current blood sugar levels and kidney function.
Common side effects of Janumet include nausea, indigestion, and headaches, though many patients find these diminish as their body adjusts to the medication. Some users may also experience a metallic taste in the mouth or mild diarrhoea when first starting the treatment.
Janumet should not be used by patients with type 1 diabetes or those with severe kidney problems, as there is a rare but serious risk of lactic acidosis. You must inform your prescriber if you have a history of pancreatitis or if you are scheduled for any imaging tests involving iodine contrast dyes.
Janumet is often preferred over taking separate tablets because it simplifies the treatment regimen and improves adherence. Unlike sulphonylureas, Janumet is less likely to cause weight gain or frequent low blood sugar (hypoglycaemia) when used as directed.
| Feature | Janumet | Metformin Alone |
|---|---|---|
| Active Ingredients | Sitagliptin & Metformin | Metformin Only |
| Blood Sugar Control | Dual-action (Higher) | Standard |
| Weight Impact | Weight Neutral | Weight Neutral/Loss |
Can I drink alcohol while taking Janumet?
You should avoid excessive alcohol consumption while taking Janumet as it can increase the risk of low blood sugar and a serious condition called lactic acidosis. It is best to discuss your alcohol intake with your healthcare provider during your consultation.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember with food, unless it is nearly time for your next scheduled dose. Never take two doses at the same time to make up for a forgotten tablet.
Is there a Patient Information Leaflet available?
Yes, every pack of Janumet includes a Patient Information Leaflet (PIL) which contains detailed data regarding the medication. You should read this thoroughly before starting your treatment to understand all safety information.
The information provided on this page is for general informational purposes only and should not replace seeing a medical professional for personalised advice. Always consult with a qualified healthcare provider before starting any new medication or making changes to your current treatment plan.
Our content is regularly reviewed by our team of medical experts to ensure it is up to date and accurate. We follow strict editorial guidelines to provide reliable information that helps you make informed decisions about your health.

