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Januvia
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Januvia is a prescription medication containing the active ingredient sitagliptin used to improve blood sugar control in adults living with type 2 diabetes mellitus.
- Clinically proven to help lower blood glucose levels in adults
- Weight-neutral treatment that fits into your daily routine
- Convenient once-daily tablet that can be taken with or without food
- Flexible care available for both NHS and private prescription patients
More information
"Januvia is a trusted treatment for adults with type 2 diabetes, typically prescribed when diet and exercise alone do not sufficiently control blood sugar or when other medications like metformin are not suitable. As a DPP-4 inhibitor, it works effectively alongside your body's natural processes to manage glucose levels without the common side effect of weight gain." - Rachael Clarke MRCPharm MFRPSI FRSPH (GPHC Number: 2061366)
You can buy Januvia through our streamlined online consultation process which is reviewed by a registered UK prescriber to ensure the treatment is safe and appropriate for you. Once your consultation is approved, your medication is dispensed and shipped from our pharmacy (GPHC Number: 9011560) in discreet packaging directly to your preferred address.
The price of Januvia varies depending on whether you are fulfilling a private prescription or an NHS repeat prescription through our service. We aim to provide a cost-effective and transparent pricing structure for all patients, ensuring you can manage your condition affordably through a regulated UK pharmacy.
We offer a range of reliable delivery options to ensure your Januvia arrives safely and promptly at your door. Our service is designed for your convenience, providing tracked shipping so you can monitor your order from the moment it leaves our pharmacy to the moment it reaches you.
Januvia is an oral medication used to manage type 2 diabetes by helping the body regulate high blood sugar levels. It belongs to a class of drugs known as dipeptidyl peptidase-4 (DPP-4) inhibitors, or "gliptins," and is specifically for adults. It is not used to treat type 1 diabetes.
The active ingredient in Januvia is sitagliptin, a selective enzyme inhibitor that prolongs the action of natural hormones in the gut. Each film-coated tablet contains sitagliptin phosphate monohydrate in various strengths to meet the specific requirements of your prescription.
User experiences with Januvia often highlight its ease of use due to the once-daily dosing and its generally well-tolerated nature compared to some other diabetes medications. Many patients appreciate that it is weight-neutral, meaning it does not typically lead to weight gain, which is a common concern in diabetes management.
The Patient Information Leaflet (PIL) provides essential details regarding the safe use, ingredients, and potential risks associated with Januvia. You should always read the leaflet provided with your medication before starting treatment to stay fully informed about your healthcare.
Januvia works by blocking the breakdown of incretin hormones in the body, which are naturally released after a meal to stimulate insulin production. By keeping these hormone levels higher for longer, the pancreas produces more insulin when blood sugar is high and the liver produces less glucose, helping to maintain a healthy balance.
You should take Januvia exactly as your doctor or healthcare provider has instructed, usually once a day at the same time. The tablets are swallowed whole with water and can be taken regardless of meal times, though maintaining a consistent routine helps ensure the medication is effective.
The standard dosage for most adults with type 2 diabetes is 100 mg taken once daily. However, your prescriber may adjust this dose if you have existing kidney problems to ensure the medication remains safe for your system.
| Condition | Typical Dosage |
|---|---|
| Standard Adult Dose | 100 mg once daily |
| Moderate Renal Impairment | 50 mg once daily |
| Severe Renal Impairment | 25 mg once daily |
Common side effects of Januvia can include headaches, upper respiratory tract infections, or a sore throat. While many people experience no side effects at all, it is important to be aware of how your body responds to the medication.
- Headaches
- Stuffy or runny nose
- Nausea or flatulence
- Swollen hands or legs
You should inform your prescriber if you have ever had pancreatitis, gallstones, or significant kidney issues before starting Januvia. This medication is not suitable for pregnant or breastfeeding women, and you should seek immediate medical attention if you experience severe, persistent abdominal pain.
Januvia is often compared to other DPP-4 inhibitors like linagliptin or metformin-based treatments. Unlike some older diabetes medications (such as sulphonylureas), Januvia has a lower risk of causing "hypos" (low blood sugar) when used on its own and is preferred by many for its weight-neutral profile.
Can I take Januvia with Metformin?
Yes, Januvia is frequently prescribed alongside metformin to provide better blood sugar control than either medication used alone. They work in different ways to help your body manage glucose levels effectively.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember, but do not take a double dose on the same day to make up for a forgotten tablet. Just resume your regular schedule the following day.
Does Januvia cause weight gain?
No, Januvia is considered weight-neutral, meaning it generally does not cause weight gain, which distinguishes it from some other classes of diabetes medication.
The information provided on this page is for general informational purposes only and should not replace seeking advice from a medical professional. Always consult with your doctor or a qualified healthcare provider for personalised medical advice regarding your condition and treatment.
Our content is regularly reviewed by our team of medical experts to ensure it remains up to date, accurate and reflects the latest clinical guidelines in the UK. We are committed to providing reliable information to help you manage your health safely.

