Kliovance

"Kliovance is typically prescribed for postmenopausal women who have not had a natural period for at least one year and require relief from symptoms such as hot flushes, night sweats and vaginal dryness. As a continuous combined treatment, it provides a steady dose of both oestrogen and progestogen to manage the transition effectively without the need for a monthly bleed." - Rachael Clarke MRCPharm MFRPSI FRSPH (GPHC Number: 2061366)

You can buy Kliovance safely through Mail my Meds by completing a convenient online consultation which is then reviewed by a registered prescriber. If your consultation is approved, your medication is dispensed and shipped directly from our pharmacy (GPHC Number: 9011560) in discreet packaging to ensure your privacy. This process allows you to order your prescription from the comfort of your home while maintaining high standards of clinical safety.

The price of Kliovance varies depending on the quantity you require for your ongoing treatment plan. At Mail my Meds, we aim to provide competitive pricing for both private and NHS prescription fulfilment. You can view the final cost for your specific selection during the checkout process after your clinical assessment is complete.

We offer various delivery methods to ensure your HRT reaches you promptly and securely. All orders are sent in plain, unbranded packaging to maintain confidentiality. Once your prescription is approved and dispensed by our pharmacy team, you will receive tracking information to monitor your shipment's progress to your chosen UK address.

Kliovance is a type of hormone replacement therapy known as 'continuous combined' HRT, used primarily to treat symptoms of the menopause and prevent bone density loss. It is specifically designed for women who have an intact uterus and have reached postmenopause, meaning it has been at least 12 months since their last natural period. By replacing the hormones your body no longer produces in high quantities, it helps stabilise your system and reduces the physical and emotional impact of the menopause.

The active ingredients in Kliovance are estradiol and norethisterone acetate, which mimic the natural female sex hormones. Each film-coated tablet contains:

• Estradiol (1mg): A natural form of the oestrogen hormone.
• Norethisterone Acetate (0.5mg): A synthetic version of the progestogen hormone.

Many users report that Kliovance effectively reduces the frequency of night sweats and hot flushes within the first few weeks of treatment. Because it is a continuous combined therapy, many patients appreciate the lack of a monthly withdrawal bleed. Some users may experience mild spotting during the first few months as their body adjusts to the hormone levels, which is a common experience with this type of HRT.

The Patient Information Leaflet (PIL) is included in every pack of Kliovance and contains essential safety data. You should read this leaflet thoroughly before starting your treatment to understand the full list of ingredients, potential interactions and storage instructions. You can also access a digital version of the PIL via the electronic Medicines Compendium (emc) website.

Kliovance works by supplementing the body with oestrogen to relieve deficiency symptoms while using progestogen to protect the lining of the womb. During menopause, oestrogen levels drop significantly; the estradiol in Kliovance replaces this lost hormone to stop symptoms like hot flushes. The norethisterone acetate (progestogen) is included because taking oestrogen alone can cause the womb lining to thicken, so the progestogen helps keep the lining thin and reduces the risk of endometrial cancer.

You should take one Kliovance tablet every day, preferably at the same time each day, to maintain a consistent level of hormones in your blood. The tablets are designed to be swallowed whole with a drink of water and can be taken with or without food. Because this is a continuous treatment, you start the next pack immediately after finishing the previous one without any breaks.

The standard dosage for Kliovance is one tablet daily, containing 1mg of estradiol and 0.5mg of norethisterone acetate. You should always follow the specific instructions provided by your prescriber. Do not attempt to double your dose if you miss a tablet; instead, take the missed dose as soon as you remember unless it is nearly time for your next one.

Like all medicines, Kliovance can cause side effects, although these often settle down after the first few months of use. Common side effects may include:

• Breast tenderness or pain
• Vaginal bleeding or spotting
• Headaches or migraines
• Fluid retention and bloating
• Mood changes or irritability

Kliovance is not suitable for everyone and should not be used if you have a history of blood clots, heart disease or certain types of cancer. You must inform your prescriber if you have liver disease, high blood pressure, diabetes or unexplained vaginal bleeding. Kliovance is not a contraceptive, so if you are under 50 or it has been less than a year since your last period, you may still need to use additional birth control.

Kliovance is often compared to other continuous combined HRT tablets, but it is known for being a lower-dose option than some alternatives. Below is a brief comparison of common HRT types:

Will Kliovance cause me to have a period?

Kliovance is a continuous combined HRT, which means you should not experience a monthly period. However, it is common to have some irregular spotting or light bleeding during the first 3 to 6 months as your body adapts to the medication.

Can I drink alcohol while taking Kliovance?

There are no known interactions between alcohol and Kliovance. However, excessive alcohol consumption can sometimes worsen certain menopause symptoms, such as hot flushes, so moderation is generally advised.

How long does it take for Kliovance to work?

Most women notice an improvement in their symptoms within a few weeks of starting treatment, though it can take up to three months to feel the full benefits. If your symptoms do not improve after this period, you should consult your healthcare provider.

The information provided on this page is for general informational purposes only and should not replace seeking advice from a medical professional for personalised care. Always consult with a doctor or pharmacist before starting any new medication to ensure it is safe and appropriate for your specific health needs.

Our content is regularly reviewed by our team of medical experts to ensure it remains up to date, accurate and aligned with current UK clinical guidelines. We are dedicated to providing reliable health information to support your well-being.