Lercanidipine

"Lercanidipine is a modern calcium channel blocker typically prescribed for patients with mild to moderate essential hypertension. It is often favoured by clinicians because its lipophilic nature allows for a gradual onset of action, which can lead to better tolerability and fewer instances of peripheral oedema compared to earlier medications in the same class." - Rachael Clarke MRCPharm MFRPSI FRSPH (GPHC Number: 2061366)

You can buy Lercanidipine through our secure online platform following a consultation with a registered prescriber to ensure the treatment is suitable for your health needs. Once your consultation is approved, your medication is dispensed and shipped directly from our UK pharmacy (GPHC Number: 9011560) in discreet packaging to maintain your privacy.

The price of Lercanidipine varies depending on whether you are fulfilling a private prescription or an NHS prescription via our electronic prescription service. While generic versions are often more cost-effective than branded alternatives like Zanidip, we provide transparent pricing throughout the checkout process before you complete your order.

We offer a range of flexible delivery services across the UK to ensure your blood pressure medication reaches you promptly and safely. All orders are sent in plain packaging, and you will receive tracking information once our pharmacy team has dispatched your prescription.

Lercanidipine is a type of medicine known as a dihydropyridine calcium channel blocker used primarily to manage hypertension. By preventing calcium from entering the muscle cells of your heart and blood vessels, it allows the vessels to relax and widen, which effectively lowers your blood pressure and reduces the long-term risk of heart disease or stroke.

The active ingredient in this medication is lercanidipine hydrochloride, which belongs to the dihydropyridine derivative group of medicines. Each tablet is formulated to release this ingredient steadily, ensuring consistent blood pressure management throughout the day.

Many users report that Lercanidipine is easier to tolerate than other blood pressure treatments, particularly regarding a lower incidence of "heavy legs" or swollen ankles. While some people may experience mild initial symptoms like flushing or headaches, these often subside as the body adjusts to the treatment over the first two weeks.

A physical copy of the Patient Information Leaflet (PIL) is included in every box of medication dispensed by our pharmacy. You should read this document thoroughly before starting your treatment, as it contains vital data on ingredients, storage and safety instructions specific to the manufacturer.

This treatment works by blocking the voltage-gated L-type calcium channels in the smooth muscle cells of the blood vessel walls. This action prevents the muscles from contracting too tightly, allowing the arteries to dilate, which lowers peripheral vascular resistance and makes it easier for your heart to pump blood around your body.

You should take your tablet once daily at the same time each day, preferably in the morning. To ensure the medicine is absorbed correctly, it is best taken at least 15 minutes before breakfast, as fatty foods can significantly alter how much of the drug enters your system.

The usual starting dose for adults is 10mg taken once a day, though a doctor may increase this to 20mg if your blood pressure requires further control. You should always follow the specific dosage instructions provided by your prescriber and never exceed the maximum daily limit of 20mg.

Like all medicines, Lercanidipine can cause side effects, although not everyone will experience them. Most side effects are mild and occur shortly after starting the medication or increasing the dose.

You must not take Lercanidipine if you have severe liver or kidney disease, or if you have recently suffered a heart attack. It is also important to avoid grapefruit and grapefruit juice while taking this medication, as it can dangerously increase the levels of the medicine in your blood. Always inform your prescriber if you are pregnant, breastfeeding or taking other medications for heart conditions or epilepsy.

Lercanidipine is often compared to other calcium channel blockers like Amlodipine or Felodipine. While all are effective at lowering blood pressure, clinical studies suggest that Lercanidipine may cause less peripheral oedema (fluid retention in the ankles) than first-generation treatments, making it a preferred choice for patients sensitive to this side effect.

Can I drink alcohol while taking Lercanidipine?

It is generally advised to limit or avoid alcohol because it can increase the blood pressure-lowering effect of the medicine, potentially making you feel dizzy or faint. If you do choose to drink, do so in moderation and monitor how you feel.

What should I do if I miss a dose?

If you forget to take your tablet, take it as soon as you remember, provided it is at least 15 minutes before your next meal. If you do not remember until the next day, skip the missed dose and continue with your regular schedule. Never take a double dose to make up for a forgotten one.

How long does it take for Lercanidipine to work?

The medication begins to work on the day you start taking it, but it may take up to two weeks of consistent use to see the full blood pressure-lowering effect. Your doctor will typically wait this long before deciding if a dose adjustment is necessary.

The information provided on this page is for general informational purposes only and should not replace seeking a consultation with a medical professional for personalised advice. Always consult your doctor or pharmacist before starting any new medication to ensure it is safe for your specific health profile.

Our content is regularly reviewed by our team of medical experts to ensure it is up to date and accurate. We strive to provide the most current clinical information to help you make informed decisions about your healthcare and treatment options.