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Levocetirizine
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Levocetirizine is a high-potency second-generation antihistamine used to effectively treat symptoms of allergic rhinitis, such as hay fever, and long-term skin allergies like urticaria by blocking the active ingredient's effect on histamine receptors.
- Fast-acting relief for hay fever and chronic idiopathic urticaria symptoms
- Non-drowsy formula designed to manage allergies without affecting daily productivity
- Prescription strength active ingredient Levocetirizine dihydrochloride
- Discreet UK delivery from our registered GPhC pharmacy following an online consultation
More information
"Levocetirizine is a potent, non-sedating antihistamine frequently prescribed for patients who require robust relief from seasonal allergies or chronic hives. In the UK, where nearly 44% of adults now suffer from at least one allergy, this treatment provides a targeted way to manage persistent symptoms like sneezing, itchy eyes and skin rashes. It is particularly valued for its higher potency compared to standard cetirizine, often allowing for effective symptom control with a once-daily 5mg dose." - Rachael Clarke MRCPharm MFRPSI FRSPH (GPHC Number: 2061366)
You can buy Levocetirizine through our secure online consultation process which is reviewed by a registered prescriber to ensure the treatment is suitable for your specific health needs. Once your consultation is approved, your medication is dispensed and shipped directly from our registered pharmacy (GPHC Number: 9011560) in discreet packaging to maintain your privacy. This service allows you to manage both new and repeat NHS or private prescriptions without the need for an in-person GP appointment.
The price of Levocetirizine varies depending on whether you are fulfilling an NHS prescription or purchasing the medication privately via our online clinic. We aim to provide a competitive, cheap Levocetirizine service for all patients while ensuring the highest standards of pharmaceutical care and safety. You can view the current pricing options during the selection stage of your online consultation.
We offer several flexible delivery options to ensure your allergy medication arrives at a time that suits your schedule. All orders are sent using tracked services so you can monitor your parcel from our pharmacy to your doorstep. If your order is approved by our medical team before the daily cut-off time, we work to process and dispatch it as quickly as possible.
Levocetirizine is an antihistamine medication used to treat symptoms associated with seasonal and perennial allergic rhinitis and chronic swelling or itching of the skin. It belongs to a group of medicines known as non-drowsy antihistamines, though it is chemically more refined than its predecessor, cetirizine. It is commonly used to treat:
- Hay fever (seasonal allergic rhinitis)
- Dust or pet allergies (perennial allergic rhinitis)
- Hives and nettle rash (urticaria)
The active substance in each tablet is Levocetirizine dihydrochloride, which is the R-enantiomer of cetirizine. This specific structure allows the medicine to bind more effectively to H1-histamine receptors in the body. Other inactive ingredients (excipients) typically include lactose monohydrate and microcrystalline cellulose. Patients with specific intolerances should check the inner packaging for a full list.
Many patients report that Levocetirizine offers a significant improvement in quality of life during high pollen seasons compared to older antihistamines. In the UK, where hay fever prevalence has risen by 33% in the last two decades, users often highlight the convenience of the once-daily dosing and the reduced incidence of "brain fog" compared to first-generation allergy treatments. However, individual results can vary based on the severity of the allergic trigger.
Every order of Levocetirizine includes a Patient Information Leaflet (PIL) which contains essential details regarding storage, usage and safety. We strongly recommend that you read this leaflet in full before starting your treatment. The PIL provides a comprehensive guide to the medication's profile and includes specific instructions for different age groups.
Levocetirizine works by blocking the H1 receptors in your body, preventing histamine from attaching to them and triggering an allergic response. Histamine is the chemical your immune system releases when it encounters an allergen like pollen or pet dander, leading to inflammation and irritation. By intercepting this process, the medication reduces the swelling in the nasal passages and limits the itching sensation on the skin.
You should take Levocetirizine exactly as instructed by your prescriber or as detailed in the patient leaflet. The tablets are usually swallowed whole with a glass of water and can be taken with or without food. To maintain a consistent level of the medicine in your bloodstream, it is best to take your dose at the same time each day, often in the evening if you find it causes mild relaxation.
The standard dosage for adults and children aged 12 years and over is one 5mg tablet taken once daily. For patients with known kidney issues, a reduced dosage may be required, which our prescribers will determine during your consultation. You should never exceed the recommended daily dose, even if your symptoms are particularly severe.
While Levocetirizine is generally well-tolerated, some people may experience side effects as their body adjusts to the medication. Common side effects affecting up to 1 in 10 people include:
- Dry mouth
- Headaches
- Mild fatigue or sleepiness
- Sore throat
Less common side effects can include abdominal pain or exhaustion. If you experience a severe allergic reaction (anaphylaxis), such as swelling of the face or difficulty breathing, seek emergency medical attention immediately.
Levocetirizine may not be suitable for everyone, particularly those with severe kidney disease or those undergoing dialysis. You should exercise caution if you have conditions that make it difficult to empty your bladder, such as an enlarged prostate or spinal cord injury. Avoid consuming alcohol while taking this medication as it may increase the risk of drowsiness and impair your alertness.
Levocetirizine is often considered more potent than loratadine and cetirizine, meaning a smaller dose can achieve similar or better results for many patients. Unlike first-generation antihistamines like chlorphenamine (Piriton), it does not cross the blood-brain barrier as easily, significantly reducing the likelihood of sedation.
| Feature | Levocetirizine | Loratadine | Cetirizine |
|---|---|---|---|
| Generation | Second (Enantiomer) | Second | Second |
| Typical Dose | 5mg Once Daily | 10mg Once Daily | 10mg Once Daily |
| Drowsiness Risk | Very Low | Low | Low |
Can I drive while taking Levocetirizine?
Most people do not feel drowsy after taking this medication. However, you should wait to see how it affects you before driving or operating machinery. If you do feel sleepy or less alert, do not drive until the effects have fully worn off.
Is Levocetirizine available on the NHS?
Yes, Levocetirizine can be prescribed on the NHS for certain conditions, and Mail My Meds can fulfil these prescriptions through our online platform. We also offer private prescriptions for those who prefer the convenience of an online consultation.
Can I take this medicine if I am pregnant?
You should consult with a healthcare professional before using any antihistamine during pregnancy or while breastfeeding. While many antihistamines are used safely, a medical review is necessary to weigh the benefits against any potential risks.
The information provided on this page is for general informational purposes only and should not replace seeking advice from a medical professional for personalised care. Always consult with your GP or a qualified pharmacist before starting a new medication to ensure it is safe for your specific health profile.
Our content is regularly reviewed by our team of medical experts to ensure it remains up to date and accurate. We adhere to strict clinical guidelines to provide reliable information that helps you make informed decisions about your health and treatments.

