Free delivery on all NHS prescriptions — order now
Mebeverine
Images for illustrative purposes only
Mebeverine is a musculotropic antispasmodic medication used to treat the symptoms of Irritable Bowel Syndrome (IBS) and related gastrointestinal spasms by relaxing the smooth muscles in the gut wall. This active ingredient, mebeverine hydrochloride, specifically targets the digestive tract to reduce abdominal pain and cramping without affecting normal bowel motility.
- Targets the smooth muscle of the gut to alleviate painful stomach cramps and intestinal spasms
- This antispasmodic medication typically begins to work within one hour of ingestion
- Available for both new and repeat NHS or private prescriptions via our digital platform
- Secure and private shipping directly to your door from our registered UK pharmacy
More information
"Mebeverine is a reliable first-line treatment for managing the physical discomfort of Irritable Bowel Syndrome (IBS) and other functional bowel disorders. It is typically prescribed to patients experiencing painful stomach cramps, persistent bloating, and irregular bowel habits. By acting directly on the intestinal muscles, it helps to normalise gut activity during a flare-up." - Rachael Clarke MRCPharm MFRPSI FRSPH (GPHC Number: 2061366)
You can buy Mebeverine safely through Mail My Meds by completing a convenient online consultation with a UK registered prescriber. Once your consultation is approved, your medication is shipped discreetly from our pharmacy (GPHC Number: 9011560) directly to your preferred address. This process ensures you receive the correct treatment for your symptoms with the professional oversight required for prescription-only medications.
The cost of Mebeverine via our online pharmacy is competitive and includes the price of the medication and the professional clinical review. While pricing may vary depending on whether you are fulfilling a private order or an NHS prescription, we aim to provide an affordable and transparent service for all patients. You can view the current pricing options during the selection process before completing your consultation.
We offer various delivery options to ensure your IBS treatment arrives when you need it most. After your prescriber approves the request, we package your medication in plain, discreet materials to maintain your privacy. You can choose from several shipping speeds at checkout, providing flexibility for both urgent needs and routine repeat prescriptions.
Mebeverine is a type of medicine known as an antispasmodic, primarily used to relieve symptoms associated with Irritable Bowel Syndrome (IBS) and similar intestinal conditions. It is specifically designed to treat stomach pain, intestinal cramps, and the persistent bloating that often accompanies functional gut disorders. In the UK, it is estimated that up to 20% of the population may experience IBS symptoms at some point, making effective management crucial for quality of life.
The active ingredient in this medication is mebeverine hydrochloride. This compound belongs to the musculotropic antispasmodic class of drugs, which means it works directly on the muscle fibres of the gastrointestinal tract. Unlike some other medications, it does not have "anticholinergic" side effects (like dry mouth or blurred vision) because its action is localised to the gut smooth muscle.
Many users report significant improvements in their daily comfort levels when using Mebeverine to manage IBS flare-ups. Patients often find it particularly helpful when taken before meals to prevent the post-eating cramps that are common with digestive sensitivities. While individual results vary, it is widely regarded as a well-tolerated option for long-term symptom management.
You should always read the Patient Information Leaflet (PIL) provided with your medication before starting treatment. The PIL contains vital data regarding specific ingredients, full lists of potential side effects, and storage instructions. If you have misplaced your leaflet, you can request a digital copy from our pharmacy team or view it on the electronic Medicines Compendium (eMC) website.
Mebeverine works by relaxing the smooth muscles in the walls of the gut and intestine, which prevents the painful spasms that cause cramping. When the intestine goes into spasm and squeezes too tightly, it results in the sharp pain associated with IBS. Mebeverine acts as a relaxant to settle these contractions. It starts to take effect roughly 60 minutes after ingestion, providing targeted relief where it is needed most.
You should take Mebeverine exactly as directed by your prescriber or as outlined on your pharmacy label. The tablets must be swallowed whole with a glass of water and should never be chewed or crushed. For the best results, it is recommended to take your dose approximately 20 minutes before a meal, as this allows the medication to be active in your system when digestion begins.
The dosage of Mebeverine depends on the specific formulation you have been prescribed. Most adults follow a standard regimen to maintain consistent levels of the medication in their system during a symptomatic period.
| Formulation | Standard Adult Dose |
|---|---|
| 135mg Tablets | One tablet taken three times daily |
| 200mg SR Capsules | One capsule taken twice daily |
Mebeverine is generally safe and well-tolerated, with most people experiencing no side effects at all. However, as with all medicines, some individuals may experience mild reactions. If you experience a severe allergic reaction (swelling of the face or difficulty breathing), you must seek medical attention immediately.
- Mild skin rash or itchy skin
- Nausea or indigestion
- Dizziness or headaches
- Heartburn or constipation
Before taking Mebeverine, you should consult your doctor if you have liver or kidney problems, or if you have developed new or worsening symptoms. This medication is not recommended for use during pregnancy or breastfeeding unless specifically advised by a healthcare professional. Ensure you inform your prescriber of any other medications you are currently taking to avoid potential interactions.
Mebeverine is often compared to other antispasmodics like Buscopan (Hyoscine butylbromide) or Alverine citrate. While they all aim to relax the gut, their active ingredients and speeds of onset differ.
- Mebeverine: Direct-acting muscle relaxant. Takes about 1 hour to work. Excellent for preventing meal-related spasms.
- Buscopan: An anticholinergic that can work within 15 minutes. May cause side effects like dry mouth in some users.
- Peppermint Oil: A natural alternative that can also relax the gut wall but may cause heartburn for some.
Can I drink alcohol while taking Mebeverine?
Yes, there are no known interactions between alcohol and Mebeverine, so you can drink moderately while using this treatment. However, be aware that alcohol can be a trigger for IBS symptoms in some individuals.
Is Mebeverine the same as Colofac?
Yes, Mebeverine is the generic name for the medication, while Colofac is a well-known brand name for the same active ingredient. Both work in the same way to treat gut spasms.
How long can I take Mebeverine for?
You should take Mebeverine for as long as your symptoms persist, which is typically 1 to 2 weeks for a flare-up. If your symptoms do not improve after two weeks, you should consult your GP.
The information provided on this page is for general informational purposes only and should not replace seeking advice from a medical professional for personalised care. Always consult with a doctor or qualified healthcare provider regarding any medical condition or treatment.
Our content is regularly reviewed by our team of medical experts to ensure it is up to date and accurate. We strive to provide reliable information that reflects the latest UK clinical guidelines and pharmaceutical standards.

