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Premique
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Premique is a combined Hormone Replacement Therapy (HRT) treatment containing conjugated estrogens and medroxyprogesterone acetate used to relieve symptoms of the menopause in women who still have an intact uterus.
- Hormone Replacement Therapy (HRT) for managing menopause symptoms
- Contains active ingredients conjugated estrogens and medroxyprogesterone acetate
- Convenient online consultation process with UK-registered prescribers
- Discreet home delivery from our registered GPhC pharmacy
More information
"Premique is a widely utilised continuous combined HRT prescribed to alleviate vasomotor symptoms such as hot flushes and night sweats while providing endometrial protection. It is typically recommended for postmenopausal women who have not had a period for at least one year to manage the physiological changes associated with decreased oestrogen levels."
- Rachael Clarke MRCPharm MFRPSI FRSPH (GPHC Number: 2061366)
You can buy Premique through Mail my Meds by completing a digital consultation that is reviewed by a UK registered prescriber to ensure the medication is suitable for your clinical needs. Once approved, your treatment is dispensed and shipped directly from our pharmacy (GPHC Number: 9011560) in discreet packaging to maintain your privacy.
The price of Premique at Mail my Meds reflects our commitment to providing affordable healthcare and includes the cost of your online clinical assessment. We offer competitive pricing for both private patients and those fulfilling NHS prescriptions through our streamlined digital platform.
We provide multiple secure delivery methods to ensure your HRT reaches you promptly and safely across the UK. All orders are tracked and packaged neutrally so that the contents of your delivery remain confidential at all times.
Premique is a medication used for Hormone Replacement Therapy to treat symptoms caused by the menopause such as vaginal dryness, mood swings and sleep disturbances. It is specifically formulated for women who have not undergone a hysterectomy as it contains both oestrogen and progestogen to protect the lining of the womb.
The active ingredients in Premique are conjugated estrogens and medroxyprogesterone acetate which work together to balance hormone levels. Conjugated estrogens replace the oestrogen the body stops producing during menopause while medroxyprogesterone acetate acts as the progestogen component to reduce the risk of endometrial hyperplasia.
Many patients report a significant reduction in the frequency of hot flushes and improved sleep quality after starting a course of Premique. Individual experiences vary and it may take several weeks of consistent use to notice the full therapeutic benefits of the treatment on menopausal symptoms.
The Patient Information Leaflet (PIL) provides essential data regarding the safe use of your medication and should be read thoroughly before starting treatment. You can find a physical copy of the leaflet inside your medication box or access a digital version through our website for detailed guidance.
Premique works by supplementing the body with synthetic hormones that mimic the natural oestrogen and progesterone produced by the ovaries. By restoring these hormone levels, the medication stabilises the body’s internal thermostat and supports various tissues that rely on oestrogen for healthy function.
You should take Premique exactly as directed by your prescriber, usually consisting of one tablet taken at the same time every day without a break between packs. It is important to swallow the tablet whole with water and it can be taken with or without food depending on your preference.
The standard dosage for Premique is one tablet daily as part of a continuous combined regimen. Your healthcare provider will determine the appropriate strength for your specific symptoms and will aim to prescribe the lowest effective dose for the shortest duration necessary.
Common side effects of Premique may include breast tenderness, headaches, vaginal spotting or changes in mood. While many of these issues resolve as your body adjusts to the hormones, you should contact a healthcare professional if you experience severe or persistent symptoms.
Premique may not be suitable for women with a history of blood clots, breast cancer, liver disease or unexplained vaginal bleeding. A full medical history must be disclosed during your consultation to ensure that HRT is a safe option for your current health status.
| Feature | Premique | Oestrogen-only HRT |
|---|---|---|
| Type | Combined (Continuous) | Oestrogen only |
| Uterus Requirement | For women with a uterus | For women who had a hysterectomy |
| Protection | Includes endometrial protection | No endometrial protection |
Can I get Premique on the NHS?
Yes, Mail my Meds can fulfil NHS prescriptions for Premique if you have a valid electronic prescription from your GP. You simply need to nominate our pharmacy as your preferred dispenser through our online portal.
Is Premique the same as Premique Low Dose?
Premique and Premique Low Dose contain the same active ingredients but in different concentrations. Your prescriber will recommend the version that best suits the severity of your symptoms and your medical history.
Will I still have a period on Premique?
As a continuous combined HRT, Premique is designed so that you do not have a regular monthly bleed, though some irregular spotting can occur during the first few months of treatment.
The information provided on this page is for general informational purposes only and should not replace seeking advice from a medical professional. Always consult with a doctor or qualified healthcare provider for personalised medical advice regarding your treatment and health condition.
Our content is regularly reviewed by our team of medical experts to ensure it remains up to date and accurate. We strive to provide the most current information based on UK clinical guidelines to help you make informed decisions about your health.
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