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Spedra
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Spedra is a fast-acting prescription medication containing the active ingredient avanafil, specifically designed to treat erectile dysfunction (ED) by improving blood flow to the penis to help men achieve and maintain a firm erection.
- Clinically proven to work in as little as 15 to 30 minutes
- Available in multiple strengths to suit individual effectiveness and tolerability
- Unlike other PDE5 inhibitors, its absorption is less affected by high-fat meals
- Fulfilled by our registered UK pharmacy with private online consultations included
More information
Spedra, which contains the potent PDE5 inhibitor avanafil, is primarily prescribed for adult men experiencing erectile dysfunction, a condition affecting approximately 1 in 5 men in the UK. This second-generation medication is frequently chosen by patients who require a faster onset of action for greater spontaneity or those who have previously experienced side effects with older treatments.
— Rachael Clarke MRCPharm MFRPSI FRSPH (GPHC Number: 2061366)You can buy Spedra online through Mail My Meds by completing a simple, confidential consultation that is reviewed by a UK-registered prescriber to ensure the medication is safe for you. Once approved, your prescription is dispensed directly from our pharmacy (GPHC Number: 9011560) and shipped in discreet, plain packaging to your preferred UK address.
The cost of Spedra varies depending on the strength and the quantity of tablets required for your treatment plan. As a branded medication, it typically commands a higher price point than generic alternatives like sildenafil, reflecting its advanced formulation for rapid absorption.
We offer several convenient delivery options to ensure you receive your medication promptly and privately across the UK. Patients can choose between standard tracked delivery, next-day delivery for urgent requirements, or collection from designated points, all utilising discreet packaging that does not mention the pharmacy or the contents.
Spedra is an oral tablet used to treat erectile dysfunction, a medical condition where a man cannot get or keep an erection firm enough for sexual activity. It belongs to a class of medicines called phosphodiesterase type 5 (PDE5) inhibitors, which work alongside sexual stimulation to relax the blood vessels in the penis, facilitating healthy blood flow.
The active substance in Spedra is avanafil, a highly selective PDE5 inhibitor. Each tablet also contains inactive excipients such as mannitol, fumaric acid, and magnesium stearate. Patients with specific allergies should refer to the internal Patient Information Leaflet for a comprehensive list of ingredients.
Many users report high satisfaction with Spedra due to its speed, with many achieving results within 20 minutes of consumption. While clinical data from the BNF indicates it is generally well-tolerated, individual experiences vary, and some men prefer it over Viagra because it allows for more spontaneous sexual encounters without the need to plan an hour in advance.
The Patient Information Leaflet (PIL) is the most important document provided with your medication, containing detailed safety data and manufacturer instructions. You should read the PIL thoroughly before taking your first dose to understand the specific risks and storage requirements for avanafil.
Spedra works by inhibiting the PDE5 enzyme, which prevents the breakdown of cyclic guanosine monophosphate (cGMP), the chemical responsible for relaxing smooth muscle and increasing blood flow during sexual arousal. By maintaining higher levels of cGMP, the medication makes it easier to achieve an erection, though it is important to note that sexual stimulation is still required for the drug to take effect.
You should take one Spedra tablet approximately 15 to 30 minutes before anticipated sexual activity, swallowing it whole with a glass of water. It can be taken with or without food, though its onset may be slightly delayed if taken shortly after a very heavy or high-fat meal.
The standard starting dose for most men is 100mg, which may be adjusted by your clinician based on your response.
- 50mg: Often prescribed if you experience minor side effects or have certain underlying health conditions.
- 100mg: The recommended starting strength for the majority of new patients.
- 200mg: The maximum dose, intended for those who did not find the 100mg dose effective.
Do not take more than one dose in any 24-hour period.
Most side effects associated with Spedra are mild and temporary, occurring as the body adjusts to the increased blood flow.
- Common (1 in 10): Headache, facial flushing, or nasal congestion.
- Uncommon: Dizziness, back pain, or indigestion.
- Rare: Priapism (an erection lasting longer than 4 hours), which requires immediate medical attention to prevent permanent tissue damage.
Spedra is not suitable for everyone and must never be taken with nitrates (often prescribed for chest pain/angina), as this can cause a life-threatening drop in blood pressure. You should exercise caution or avoid use if you have severe heart or liver problems, have recently suffered a stroke or heart attack, or have certain rare inherited eye diseases like retinitis pigmentosa.
Spedra is distinct from other ED medications like Viagra (sildenafil) or Cialis (tadalafil) primarily due to its speed of onset and its selective nature. While Cialis offers a longer window of effectiveness (up to 36 hours), Spedra is the preferred choice for those who value the fastest possible results within a 4 to 6-hour window.
| Feature | Spedra (Avanafil) | Viagra (Sildenafil) | Cialis (Tadalafil) |
|---|---|---|---|
| Onset Time | 15-30 Mins | 30-60 Mins | 30-60 Mins |
| Duration | 4-6 Hours | 4-6 Hours | Up to 36 Hours |
Can I take Spedra with alcohol?
While a small amount of alcohol is unlikely to cause issues, excessive drinking can make it harder to get an erection and may increase the risk of side effects like dizziness or low blood pressure.
Is Spedra available over-the-counter?
No, Spedra is a prescription-only medication (POM) in the UK and cannot be bought over-the-counter. However, you can obtain it via our online consultation service.
Does Spedra work the first time?
Many men find it effective on the first use, but it is recommended to try the medication at least 8 times before deciding if it works for you, as anxiety or timing can impact results.
The information provided on this page is for general informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or another qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.
At Mail My Meds, our clinical content is regularly reviewed and updated by our team of medical experts and pharmacists to ensure all information remains accurate, evidence-based, and aligned with current UK healthcare guidelines from the NHS and NICE.
