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Spiolto Respimat
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Spiolto Respimat is a prescription-only maintenance treatment for adult patients with Chronic Obstructive Pulmonary Disease (COPD) that utilises the active ingredients tiotropium and olodaterol to improve long-term breathing stability.
- Combines two long-acting bronchodilators to open airways for 24 hours
- Designed for the daily management of Chronic Obstructive Pulmonary Disease (COPD) symptoms
- Uses the Respimat Soft Mist technology for easy inhalation without forceful breathing
- Fulfilled by a registered UK pharmacy with tracked, discreet home delivery
More information
"Spiolto Respimat is a foundational long-acting treatment typically prescribed for adults living with Chronic Obstructive Pulmonary Disease, including those managing chronic bronchitis and emphysema. By combining an anticholinergic with a long-acting beta2-agonist, it provides a dual-action approach to keep the airways open throughout the day and night. It is important to remember that this is a maintenance medication and is not intended for the relief of sudden, acute breathlessness." - Rachael Clarke MRCPharm MFRPSI FRSPH (GPHC Number: 2061366)
You can buy Spiolto Respimat safely through the Mail my Meds online platform by completing a brief clinical consultation to ensure the treatment is suitable for your specific health needs. Once your consultation is reviewed and approved by one of our UK-registered prescribers, your prescription will be electronically sent to our pharmacy (GPHC Number: 9011560) for dispensing. Your medication is then shipped in discreet, secure packaging directly to your preferred UK address, providing a convenient alternative to traditional high-street pharmacy visits.
The cost of Spiolto Respimat at Mail my Meds is competitive and reflects our commitment to providing accessible healthcare across the UK. While prices for private prescriptions may vary based on current supplier rates, we aim to offer transparent pricing that includes the cost of your clinical review and tracked delivery. For patients with a valid NHS exemption or those using our NHS prescription fulfilment service, standard NHS levy charges will apply where applicable.
We offer several reliable delivery options to ensure you receive your COPD medication promptly and securely. Our service includes tracked shipping methods that allow you to monitor your parcel from our pharmacy to your doorstep. All orders are dispatched in plain packaging to maintain patient confidentiality and discretion, with options for expedited delivery available for those who require their maintenance inhaler urgently.
Spiolto Respimat is an inhalation solution used for the long-term maintenance treatment of Chronic Obstructive Pulmonary Disease (COPD) in adults to help ease persistent breathing difficulties. COPD is a progressive lung condition, often encompassing chronic bronchitis and emphysema, which causes the airways to become narrowed and inflamed. This medication is part of a class of drugs known as bronchodilators, which work to relax the muscles in the lungs, making it easier for air to move in and out.
The active ingredients in Spiolto Respimat are tiotropium (as bromide monohydrate) and olodaterol (as hydrochloride), which work together to provide sustained bronchodilation. Tiotropium is a long-acting muscarinic antagonist (LAMA), while olodaterol is a long-acting beta2-agonist (LABA). These two components target different receptors in the airways to maximise the relaxation of the smooth muscles in the lungs for a full 24-hour period.
Many users report that Spiolto Respimat helps significantly with daily symptom control, particularly in reducing the frequency of shortness of breath and morning coughing fits. Because it uses the Respimat "Soft Mist" technology, patients who struggle with the forceful coordination required for traditional dry powder inhalers often find it easier to use. Clinical data in the UK suggests that approximately 1.4 million people are living with diagnosed COPD, and effective maintenance therapy is a key factor in improving their overall quality of life and exercise tolerance.
The Patient Information Leaflet (PIL) contains essential safety data and technical instructions that every patient should read before starting their treatment. It provides a comprehensive breakdown of excipients, such as benzalkonium chloride, and detailed guidance on the preparation of the Respimat device. You can access the digital version of the PIL through our website or find the physical copy included inside your product packaging.
Spiolto Respimat works by combining two different mechanisms to widen the airways and prevent the muscles around the bronchial tubes from tightening. The tiotropium component blocks the M3 muscarinic receptors to prevent bronchoconstriction, while the olodaterol component stimulates beta2-adrenoceptors to actively trigger muscle relaxation. This dual approach is often more effective than using a single-ingredient inhaler for patients whose symptoms remain persistent on a LAMA or LABA alone.
To use Spiolto Respimat correctly, you must first prepare the re-usable Respimat device by inserting the cartridge and priming it until a visible mist is released. Once the device is ready, you should follow the "Turn, Open, Press" (TOP) sequence: turn the clear base until it clicks, open the cap, breathe out away from the inhaler, and then press the dose-release button while taking a slow, deep breath in. It is vital to hold your breath for about 10 seconds after inhalation to ensure the medication reaches deep into the lungs.
The standard dosage for Spiolto Respimat is two puffs once daily, taken at the same time each day to maintain a consistent level of medication in your system. You should not exceed this dose, as taking more than two puffs in a 24-hour period does not increase the benefit and may increase the risk of adverse effects. Consistency is key. This medication must be used every day, even when you feel your breathing is clear, to provide continuous protection against COPD flare-ups.
Like all medicines, Spiolto Respimat can cause side effects, although not everyone will experience them during their treatment. Common side effects may include a dry mouth, mild cough, or a sore throat as the body adjusts to the bronchodilators. Less common but more serious effects can include a rapid or irregular heartbeat, blurred vision, or difficulty passing urine. If you experience any of these, you should consult a healthcare professional immediately.
Spiolto Respimat should be used with caution if you have a history of heart problems, high blood pressure, glaucoma, or prostate issues. It is strictly not for use in treating asthma, as the safety profile for asthma patients has not been established for this specific combination. Additionally, you must notify your prescriber if you are pregnant, breastfeeding, or taking other medications, particularly other anticholinergics or beta-blockers, as these can interact with your treatment.
Spiolto Respimat is often compared to other dual-action LAMA/LABA inhalers, such as Anoro Ellipta or Ultibro Breezhaler, which also aim to improve lung function in COPD patients. The primary difference often lies in the delivery mechanism. While many competitors use dry powder, Spiolto uses a soft mist which is less dependent on the patient's inspiratory flow rate.
| Feature | Spiolto Respimat | Dry Powder Inhalers (DPI) |
|---|---|---|
| Active Ingredients | Tiotropium / Olodaterol | Varies (e.g., Umeclidinium / Vilanterol) |
| Delivery Method | Soft Mist (Slow moving) | Dry Powder (Requires fast breath) |
| Frequency | Once Daily | Usually Once Daily |
Can I use Spiolto Respimat for a sudden asthma attack?
No, Spiolto Respimat is not a rescue inhaler and should never be used to treat sudden attacks of breathlessness or wheezing. You must always have a separate "reliever" inhaler, such as Salbutamol, available for emergency symptom relief.
How long does one Respimat cartridge last?
A single cartridge is designed to provide a 30-day supply of medication when used at the recommended dose of two puffs once daily. The device features a dose indicator that turns red when you are nearing the end of the supply.
Is this treatment available on the NHS?
Yes, Spiolto Respimat is available for NHS patients in the UK. Mail my Meds can fulfil your repeat NHS prescriptions and deliver them directly to your home for added convenience.
The information provided on this page is for general informational purposes only and should not replace seeking advice from a medical professional for personalised care. Always consult with your doctor or a qualified healthcare provider regarding any medical condition or treatment plan.
Our content is regularly reviewed by our team of medical experts to ensure it is up to date, accurate, and aligned with current UK clinical guidelines. We strive to provide reliable information to help you make informed decisions about your respiratory health.

