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Xigduo
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Xigduo is a combination prescription medication used to improve glycaemic control in adults with Type 2 diabetes by utilising the active ingredients Dapagliflozin and Metformin hydrochloride.
- Effective dual-action treatment for managing Type 2 diabetes.
- Contains active ingredients Dapagliflozin and Metformin
- Convenient online clinical consultation with a UK prescriber
- Discreet tracked delivery from our registered GPhC pharmacy
More information
"Xigduo is a frequently prescribed oral treatment for adults living with Type 2 diabetes, specifically used when diet and exercise alone do not provide sufficient blood sugar control. By combining a sodium-glucose co-transporter 2 (SGLT2) inhibitor with a biguanide, it offers a comprehensive approach to managing glucose levels." - Rachael Clarke MRCPharm MFRPSI FRSPH (GPHC Number: 2061366)
You can buy Xigduo through Mail my Meds by completing a straightforward online consultation that is reviewed by a UK registered prescriber. Once your clinical assessment is approved, your medication is dispensed and shipped directly from our registered pharmacy (GPHC Number: 9011560) in discreet packaging to ensure your privacy and convenience.
The cost of Xigduo at Mail my Meds reflects our commitment to providing affordable healthcare and includes the price of the medication, the clinical review by our prescribing team and secure delivery. We aim to remain competitive with other UK online pharmacies while ensuring the highest standards of patient safety and pharmaceutical care.
We provide a range of reliable delivery options to ensure your Type 2 diabetes medication reaches you safely and promptly across the UK. You can select your preferred shipping method during the checkout process, and all orders are sent using tracked services so you can monitor your parcel from our pharmacy to your doorstep.
Xigduo is a prescription-only medicine used to treat Type 2 diabetes mellitus in adults, helping to lower blood sugar levels and reduce the risk of serious complications. It is typically used alongside a healthy diet and regular physical activity, and it may be prescribed alone or in combination with other glucose-lowering medications like insulin.
Xigduo contains two primary active ingredients that work in different ways to manage blood glucose: Dapagliflozin and Metformin hydrochloride. Dapagliflozin belongs to the SGLT2 inhibitor class, while Metformin is a biguanide, and together they provide a synergistic effect for patients who require more than one type of medication.
Many patients report positive experiences with Xigduo, often noting the convenience of taking one combined tablet rather than two separate medications for their diabetes. User feedback frequently highlights improved HbA1c levels, though experiences can vary, and it is important to discuss your progress and any concerns with your healthcare provider during regular check-ups.
The Patient Information Leaflet (PIL) is included in every box of Xigduo and contains essential details regarding storage, usage and safety. You should read this document thoroughly before starting your treatment. A digital version is also available on the electronic Medicines Compendium (eMC) website for easy reference at any time.
Xigduo works through a dual-action mechanism where Dapagliflozin encourages the kidneys to remove excess glucose through urine and Metformin reduces the amount of sugar produced by the liver. Additionally, Metformin helps the body respond better to the insulin it naturally produces, making the overall management of Type 2 diabetes more effective.
You should take Xigduo exactly as directed by your prescriber, usually twice daily with food to minimise the risk of stomach upset or digestive discomfort. Swallow the tablets whole with a glass of water and do not crush or chew them, as this can interfere with the way the medication is absorbed into your system.
The dosage of Xigduo is tailored to your specific medical needs and current blood sugar levels, though it is commonly taken as one tablet twice a day. Your prescriber will determine the correct strength based on your previous experience with Metformin or Dapagliflozin to ensure the treatment is both safe and effective for you.
Common side effects of Xigduo may include nausea, digestive changes, or an increased risk of urinary tract infections due to the way the medication removes sugar from the body. While many people experience no issues, it is important to stay hydrated and contact a medical professional if you notice any persistent or severe symptoms while taking the medication.
Xigduo is not suitable for everyone, particularly those with severe kidney or liver problems, or individuals at risk of diabetic ketoacidosis. You must inform your prescriber of your full medical history and any other medications you are taking, as certain conditions or treatments can interact with Xigduo and affect its safety profile.
Xigduo is often preferred over single-agent therapies because it combines two established treatments into one tablet, improving patient adherence and blood sugar control. Unlike some older diabetes medications, the inclusion of an SGLT2 inhibitor like Dapagliflozin may also offer additional cardiovascular benefits for certain patients.
| Feature | Xigduo (Combination) | Metformin (Single) | Dapagliflozin (Single) |
|---|---|---|---|
| Active Ingredients | Two | One | One |
| Primary Action | Dual mechanism | Reduces liver glucose | Glucose removal via urine |
| Convenience | High (1 tablet) | Standard | Standard |
Can I drink alcohol while taking Xigduo?
It is generally advised to avoid excessive alcohol consumption while taking Xigduo as it can increase the risk of lactic acidosis, a rare but serious side effect. Speak with your prescriber about what constitutes a safe level of alcohol for your specific circumstances.
Do I need an NHS prescription for Xigduo?
While Xigduo is available via the NHS, you can also obtain it through a private prescription at Mail my Meds following a successful online clinical consultation with our registered prescribing team.
Is Xigduo suitable for weight loss?
Xigduo is primarily a treatment for Type 2 diabetes, but some patients may experience weight loss as a secondary effect of the Dapagliflozin component. However, it should not be used as a primary weight loss medication.
The information provided on this page is for general informational purposes only and should not replace seeking advice from a medical professional for personalised care. Always consult with your doctor or a qualified healthcare provider regarding any medical condition or treatment plan.
Our content is regularly reviewed by our team of medical experts to ensure it is up to date, accurate and reflects the latest clinical guidelines in the UK. We are dedicated to providing reliable information to help you make informed decisions about your health and wellbeing.
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