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Zelleta
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Zelleta is a progestogen-only contraceptive pill containing the active ingredient desogestrel 75 micrograms, which is primarily used to prevent pregnancy in women who may be sensitive to oestrogen.
- Contains desogestrel to provide reliable protection against pregnancy
- A progestogen-only pill (POP) suitable for those sensitive to oestrogen
- Features a 12-hour window for missed doses compared to traditional mini pills
- Taken every day without a break to maintain consistent hormone levels
More information
"Zelleta is a progestogen-only pill (POP), commonly referred to as the 'mini pill', which is typically prescribed as a daily oral contraceptive to prevent pregnancy. It is frequently recommended for patients who cannot use combined pills due to oestrogen sensitivity, breastfeeding, or specific health risks. As a desogestrel-based medication, it works effectively by inhibiting ovulation and altering cervical mucus to prevent fertilisation." - Rachael Clarke MRCPharm MFRPSI FRSPH (GPHC Number: 2061366)
You can buy Zelleta through our streamlined online consultation process which is reviewed by a UK registered prescriber to ensure the treatment is safe and appropriate for you. Once your consultation is approved, your medication is dispensed and shipped directly from our pharmacy (GPHC Number: 9011560) using discreet packaging for your privacy. This service allows you to manage your reproductive health conveniently without needing to visit a GP in person for every repeat prescription.
The cost of Zelleta is kept competitive to ensure affordable access to essential contraceptive care for all patients. While prices may vary based on the quantity required for your treatment plan, we provide transparent pricing throughout the checkout process. Choosing an online pharmacy for your prescription can often be a cost-effective way to manage regular medication needs.
We provide a range of reliable delivery options to ensure your contraceptive pills arrive when you need them. All orders are sent in plain, unbranded packaging to maintain total discretion for our patients. You can select your preferred shipping method at the final stage of your order to suit your schedule and urgency.
Zelleta is a brand of hormonal contraception known as a progestogen-only pill (POP) that is used to prevent pregnancy. Unlike combined oral contraceptives, it does not contain oestrogen, making it a preferred choice for women who are breastfeeding or those with a higher risk of blood clots. It is a highly effective method of birth control when taken consistently at the same time each day.
The active ingredient in this medication is desogestrel, a synthetic progestogen that mimics the natural female hormone progesterone. Each tablet contains 75 micrograms of desogestrel. This specific dose is sufficient to consistently prevent the ovaries from releasing an egg, which distinguishes it from older types of mini pills.
Many users report that Zelleta is easy to incorporate into their daily routine due to the simple one-tablet-a-day cycle. Common feedback mentions changes in menstrual patterns, with some users experiencing lighter periods or no bleeding at all. While individual experiences vary, the majority of patients find it a tolerable and convenient alternative to oestrogen-based pills.
The Patient Information Leaflet (PIL) provides comprehensive details regarding the safe use, potential risks and storage of your medication. It is essential to read the leaflet provided in your pack before starting the treatment. You can also access the digital version of the Zelleta PIL through the electronic Medicines Compendium (eMC) for the most up-to-date safety data.
Zelleta works primarily by preventing ovulation, which is the release of an egg from the ovaries each month. In addition to stopping ovulation, the hormone desogestrel thickens the mucus in the cervix, making it difficult for sperm to reach an egg. It also thins the lining of the womb (endometrium), reducing the likelihood that a fertilised egg could implant itself.
You should take one tablet of Zelleta at approximately the same time every day to maintain maximum effectiveness. The tablets are swallowed whole with water and should be taken continuously without any breaks between packs. Follow the arrows and days of the week printed on the blister strip to help you keep track of your daily doses.
The standard dosage for this contraceptive is one 75 microgram tablet taken once daily. It is vital not to skip doses, as the effectiveness of the mini pill relies on maintaining a consistent level of progestogen in your system. If you are starting the pill for the first time, your prescriber will advise you on the best day to begin your first pack.
Like all medications, Zelleta can cause side effects, although not everyone will experience them. Most symptoms are mild and often resolve as your body adjusts to the hormones. Common side effects may include:
- Irregular vaginal bleeding or spotting
- Changes in mood or libido
- Headaches
- Nausea
- Acne or skin changes
- Breast tenderness
Before taking Zelleta, you must inform your prescriber if you have a history of liver disease, breast cancer or unexplained vaginal bleeding. While the risk is lower than with combined pills, hormonal contraceptives can slightly increase the risk of blood clots (thrombosis). This medication contains lactose, so patients with specific sugar intolerances should exercise caution and consult their pharmacist.
Zelleta is often compared to other desogestrel pills like Cerazette or Cerelle, as they contain the same active ingredient and work in identical ways. The table below highlights the differences between the two main types of mini pills available in the UK:
| Feature | Zelleta (Desogestrel) | Traditional Mini Pill |
|---|---|---|
| Missed Pill Window | 12 hours | 3 hours |
| Stops Ovulation | Yes (in most cases) | Not always |
| Oestrogen Content | None | None |
What should I do if I miss a pill?
If you are less than 12 hours late, take the missed pill immediately and continue your pack as normal. You will still be protected. If you are more than 12 hours late, take the pill but use additional protection like condoms for the next two days, as your contraceptive coverage may be reduced.
Can I take Zelleta while breastfeeding?
Yes, Zelleta is generally considered safe to use while breastfeeding as it does not contain oestrogen, which can sometimes affect milk production. Small amounts of desogestrel may pass into breast milk, but studies have shown no significant impact on the health or development of the infant.
Will Zelleta stop my periods?
It is common for periods to become irregular, lighter or stop completely while taking a progestogen-only pill. This is a normal response to the hormone and is not harmful, though you should take a pregnancy test if you are concerned after missing a period while not taking the pill perfectly.
The information provided on this page is for general informational purposes only and should not replace seeking advice from a medical professional. Always consult with a doctor or qualified healthcare provider for personalised medical advice regarding your contraception and health needs.
Our content is regularly reviewed by our team of medical experts to ensure it remains up to date and accurate. We strive to provide reliable information that reflects current UK clinical guidelines and pharmaceutical standards.

