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Zidoval
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Zidoval is a prescription-only vaginal gel used to treat bacterial vaginosis by utilising the active ingredient metronidazole to restore natural vaginal balance.
- Treats bacterial vaginosis (BV) directly at the site of infection
- Contains the active ingredient metronidazole to clear harmful bacteria
- Includes five disposable applicators for a convenient five-day course
- Professional online consultation with secure, private home delivery
More information
"Zidoval vaginal gel is a highly effective, targeted antibiotic treatment specifically prescribed for adult women to clear symptomatic bacterial vaginosis. By delivering the active medication directly to the vaginal mucosa, it effectively neutralises the anaerobic bacteria responsible for the infection while reducing the likelihood of systemic side effects often associated with oral antibiotics."
- Rachael Clarke MRCPharm MFRPSI FRSPH (GPHC Number: 2061366)
You can buy Zidoval safely through Mail my Meds by completing a brief online consultation that is reviewed by a UK registered prescriber. If your consultation is approved, your medication is shipped directly from our pharmacy (GPHC Number: 9011560) in discreet, plain packaging to ensure your privacy. This process eliminates the need for a face-to-face appointment while maintaining the highest standards of patient safety and clinical oversight.
The price of Zidoval reflects the cost of the medication, the clinical review by our prescribing team, and our secure dispensing service. We aim to provide a competitive and transparent pricing structure for all our patients seeking private prescriptions. You can view the current price for your required quantity during the selection process before you finalise your order.
We offer various delivery methods to suit your schedule, ranging from standard shipping to expedited next-day services. All orders are sent using tracked couriers to ensure you can monitor your package from our pharmacy to your doorstep. Every shipment is packaged discreetly with no mention of the contents or the pharmacy on the outer label.
Zidoval is a topical antibiotic gel used specifically for the treatment of bacterial vaginosis (BV) in women. It is designed to target anaerobic bacteria, such as Gardnerella vaginalis, which can cause an imbalance in the vaginal flora. Common symptoms of BV include a thin, greyish-white discharge and a noticeable "fishy" odour, both of which Zidoval helps to resolve by clearing the underlying infection.
The active substance in this medication is metronidazole, a potent antibacterial agent. Each gram of Zidoval gel contains 7.5mg of metronidazole (0.75% w/w). The formula also includes inactive ingredients like propylene glycol and purified water to ensure the gel is comfortable to apply and maintains a pH level compatible with the vaginal environment.
Most users report a significant reduction in BV symptoms within the first two to three days of the five-day treatment course. Many patients prefer the gel over oral tablets because it is applied locally, which often results in fewer gastrointestinal issues like nausea. Consistency is key, and users who complete the full course as directed typically see high success rates in clearing the infection.
The Patient Information Leaflet (PIL) is included in every box of Zidoval and should be read thoroughly before starting your treatment. It contains vital details regarding usage instructions, a full list of ingredients, and specific safety warnings. You can also access a digital version of the leaflet on our website or via the electronic Medicines Compendium (eMC).
Zidoval works by entering the cells of anaerobic bacteria and disrupting their DNA, which prevents them from growing and multiplying. By reducing the population of these harmful bacteria, the gel allows the "good" bacteria (Lactobacilli) to repopulate the area. This process restores the natural, slightly acidic pH of the vagina, which is essential for long-term health and prevents the infection from returning.
You should use Zidoval once daily, ideally at bedtime, for five consecutive days using the disposable applicators provided. Using the gel at night helps keep the medication in place for longer, improving absorption and reducing leakage. Always wash your hands before and after application, and ensure you use a fresh applicator for every dose to maintain hygiene.
The standard adult dosage is one 5g application (one full applicator) inserted into the vagina once a day for five days. It is important to complete the entire five-day course even if your symptoms disappear sooner. Stopping treatment early can allow the remaining bacteria to multiply, potentially leading to a recurrence of the infection.
While Zidoval is generally well-tolerated because it is a local treatment, some users may experience mild side effects. These can range from localised irritation to slight systemic effects if a small amount of the antibiotic is absorbed into the bloodstream.
| Frequency | Possible Side Effects |
|---|---|
| Common | Headaches, dizziness, stomach cramps, metallic taste, or vaginal thrush. |
| Uncommon | Nausea, fatigue, darkened urine, or skin dryness. |
You must avoid drinking alcohol during your treatment and for at least 48 hours after your final dose to prevent a "disulfiram-like" reaction. This reaction can cause severe nausea, vomiting, and flushing. Additionally, Zidoval should not be used during your period, and you should avoid using tampons, douches, or other vaginal products while completing your course.
Zidoval is often compared to oral metronidazole tablets and clindamycin creams, offering a balance of efficacy and convenience. Clinical data suggests that topical metronidazole is as effective as oral forms but typically results in fewer digestive side effects.
- Zidoval Gel: Applied once daily for 5 days. Localised action with fewer systemic side effects.
- Oral Metronidazole: Usually taken twice daily for 7 days. Highly effective but may cause more nausea.
- Lactic Acid Gels: Available over-the-counter. Useful for pH balance but less effective than antibiotics for active infections.
Can I have sex while using Zidoval?
It is recommended to avoid sexual intercourse until you have finished the treatment course and the infection has completely cleared. Sex can irritate the infected tissue and potentially interfere with the effectiveness of the gel.
Can Zidoval cause thrush?
Yes, because Zidoval is an antibiotic, it can sometimes kill the healthy bacteria that prevent yeast overgrowth, leading to a thrush infection. If you notice thick, white discharge or intense itching, you may need a separate antifungal treatment.
What if my period starts during treatment?
You should not use Zidoval while you are menstruating as the blood flow can wash the gel away. If your period starts, pause the treatment and resume it once your period has finished, or consult our prescriber for advice.
The information provided here is for general informational purposes only and must not replace seeking a medical professional for personalised advice. Always consult with a doctor or pharmacist to ensure a specific treatment is suitable for your individual health needs and to confirm a diagnosis before starting any medication.
Our content is regularly reviewed by our team of medical experts to ensure it remains up to date, accurate, and aligned with current UK clinical guidelines. We prioritise provide reliable information to help you make informed decisions about your healthcare and treatment options.

