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Zomig Nasal Spray
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Zomig Nasal Spray is an acute migraine treatment containing the active ingredient zolmitriptan, a selective serotonin receptor agonist designed to alleviate headache pain and associated symptoms like photophobia and nausea.
- Fast-acting relief typically starts within 15 minutes of use
- Non-oral formula ideal for patients experiencing nausea or vomiting
- Targeted treatment for acute migraine attacks with or without aura
- Discreet delivery from our registered UK online pharmacy
More information
"Zomig Nasal Spray is a clinically proven medication typically prescribed for the acute treatment of migraine headaches with or without aura in adults and adolescents. As a triptan, it works by targeting the physiological changes in the brain that occur during an attack, providing a rapid alternative for those who find tablets difficult to swallow or suffer from gastric upset during a migraine." - Rachael Clarke MRCPharm MFRPSI FRSPH (GPHC Number: 2061366)
You can buy Zomig Nasal Spray through our secure online platform following a clinical assessment by a registered prescriber. The process involves a brief online consultation to ensure the medication is safe and appropriate for your specific health needs. Once approved, your order is fulfilled and shipped directly from our registered pharmacy (GPHC Number: 9011560) in discreet packaging to ensure your privacy.
The price of Zomig Nasal Spray reflects its status as a branded, fast-acting triptan treatment. While costs may vary depending on the quantity required for your prescription, we aim to provide competitive pricing for all our private and NHS prescription services. You can view the current pricing at the top of this page before starting your consultation.
We offer several reliable delivery methods to ensure you receive your migraine treatment as quickly as possible. All orders are sent via tracked services, with options for standard or expedited shipping available at checkout. Our goal is to provide a seamless transition from your online consultation to receiving your medication at your doorstep.
Zomig Nasal Spray is a prescription medication used for the acute treatment of migraine attacks, specifically designed to be absorbed through the nasal mucosa for rapid effect. It belongs to a group of medicines known as 5HT1-receptor agonists (triptans). It is used to treat the headache phase of a migraine and associated symptoms like sensitivity to light and sound, but it is not a preventative medicine and will not reduce the frequency of your attacks.
The active ingredient in Zomig Nasal Spray is zolmitriptan. Each single-use device typically delivers a 5mg dose of zolmitriptan in a buffered aqueous solution, allowing the medicine to enter the bloodstream quickly through the lining of the nose, bypassing the digestive system.
Many patients report high levels of satisfaction with Zomig Nasal Spray due to its speed of action, with many experiencing significant pain relief within 15 to 30 minutes. Users who experience severe nausea during migraines often prefer this nasal format over oral tablets. While some mention a temporary unusual taste in the back of the throat after use, the overall consensus highlights its effectiveness in restoring normal daily function during an attack.
The Patient Information Leaflet (PIL) is included in every box of medication and provides comprehensive details on usage, safety and ingredients. It is essential to read this leaflet before using the spray for the first time. You can also access a digital version of the PIL through the electronic Medicines Compendium (eMC) website.
Zolmitriptan works by stimulating serotonin receptors in the brain, which causes the widened blood vessels associated with migraines to narrow. It also helps to reduce the release of natural substances that cause inflammation and pain signals. By reversing these changes, the medication helps to alleviate the throbbing headache and other symptoms of the attack.
To use the treatment, you should first blow your nose gently to clear the nasal passages. Remove the protective cap, sit or stand in a comfortable position, and insert the nozzle into one nostril while blocking the other with your finger. Press the plunger firmly while breathing in gently through your nose, then keep your head tilted back for a few seconds to allow the medicine to be absorbed.
The standard dose is one 5mg spray into one nostril at the first sign of a migraine headache. You should follow the specific instructions provided by your prescriber, but the general guidelines are as follows:
- Initial Dose: One 5mg spray as soon as the headache starts.
- Second Dose: If the migraine returns within 24 hours, a second dose can be taken, provided it is at least 2 hours after the first.
- Maximum Dose: Do not exceed 10mg (two 5mg sprays) in any 24-hour period.
Like all medicines, Zomig can cause side effects, although not everyone gets them. Most side effects are mild and resolve quickly as the medication leaves your system.
| Frequency | Common Side Effects |
|---|---|
| Very Common | Unusual taste in the mouth |
| Common | Dizziness, sleepiness, dry mouth, nausea, tingling sensations, or a feeling of heaviness/tightness in the throat or chest |
| Uncommon | Increased heart rate or slightly higher blood pressure |
Zomig Nasal Spray is not suitable for everyone, particularly those with certain cardiovascular conditions. You should not use this medication if you have a history of heart disease, heart attack, stroke, or uncontrolled high blood pressure. It is also important to mention if you are taking other medications, such as SSRIs or MAOIs, during your consultation, as these can interact with zolmitriptan.
Zomig is often compared to other triptans like Sumatriptan or Rizatriptan. While all triptans work similarly, the nasal spray format of Zomig provides a distinct advantage in absorption speed and convenience for those with gastric symptoms.
- Zomig Nasal Spray: Faster onset (15 mins) than most tablets. Avoids the stomach.
- Sumatriptan Tablets: Often the first-line treatment. May take 30-60 minutes to work.
- Zomig Rapimelt: Orally disintegrating tablets that dissolve on the tongue. Useful but still absorbed via the gut.
Can I use Zomig to prevent a migraine?
No, Zomig Nasal Spray is only intended to treat a migraine once it has already started. It will not prevent an attack from occurring if taken during the "aura" phase or before symptoms develop.
Can I take Zomig with other painkillers?
You can often take Zomig alongside simple analgesics like paracetamol or NSAIDs like ibuprofen if advised by your doctor. However, you must not take it with other triptans or ergotamine-containing medicines.
Does it matter which nostril I use?
No, you can use either nostril for the dose. If you have a blocked nose due to a cold, the absorption might be slightly affected, so ensure your nasal passage is as clear as possible before use.
The information provided on this page is for general informational purposes only and should not replace seeking advice from a medical professional. Always consult with your doctor or a qualified healthcare provider for personalised medical advice regarding your condition and treatment options.
Our content is regularly reviewed by our team of medical experts to ensure it remains up to date, accurate and aligned with current UK clinical guidelines. We prioritise providing reliable information to help you manage your health effectively.

