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Lariam
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Lariam is a prescription-only antimalarial treatment containing the active ingredient mefloquine, primarily used to prevent and treat malaria caused by Plasmodium falciparum in travellers visiting high-risk regions.
- Convenient one-tablet weekly regimen for easier adherence compared to daily alternatives
- Effective for malaria prevention in regions with high chloroquine resistance
- Specifically used for travellers visiting high-risk tropical and subtropical destinations
- Access a safe online consultation with a registered UK clinician to ensure suitability
More information
"Lariam is typically prescribed to prevent or treat malaria, a serious and potentially life-threatening disease transmitted by infected mosquitoes. It is particularly effective for those travelling to areas where the malaria parasite has developed resistance to other common medications. Because it only needs to be taken once a week, it is often a preferred choice for long-term travellers, though a thorough medical assessment is required to ensure it is safe for your specific health history." - Rachael Clarke MRCPharm MFRPSI FRSPH (GPHC Number: 2061366)
You can buy Lariam through Mail My Meds by completing a simple and convenient online consultation with a registered prescriber. Once your consultation is approved, your medication is shipped directly from our pharmacy (GPHC Number: 9011560) in discreet, plain packaging to ensure your privacy. This process allows you to secure your travel medication without needing to visit a GP in person, provided the treatment is clinically suitable for you.
The cost of Lariam at Mail My Meds is competitive and varies based on the length of your trip and the number of tablets required for a full course. We aim to provide affordable access to malaria prophylaxis while maintaining the highest standards of pharmaceutical care. You can view the current pricing for different quantities during the selection process before you begin your consultation.
We offer various delivery options to ensure you receive your antimalarial tablets well before your departure date. Once our registered prescriber approves your order, it is dispatched from our UK-based pharmacy using reliable courier services. You will receive tracking information so you can monitor your parcel's journey to your doorstep.
Lariam is a brand-name medication used for the chemoprophylaxis (prevention) and curative treatment of malaria. Malaria is a parasitic infection spread through the bites of Anopheles mosquitoes, common in many parts of Africa, South America and Asia. Lariam is often recommended for regions where the malaria parasite is resistant to other drugs like chloroquine.
The active ingredient in Lariam is mefloquine hydrochloride, with each tablet typically containing 250mg of the substance. Mefloquine is a quinoline methanol derivative that works specifically against the blood stages of the malaria parasite.
Many users find Lariam to be a highly convenient option due to its weekly dosing schedule, which reduces the likelihood of forgetting a dose. While most travellers tolerate the medication well, some users report vivid dreams or mild nausea. It is important to monitor how you feel, especially if you are taking it for the first time.
Every pack of Lariam includes a Patient Information Leaflet (PIL) which provides comprehensive details on how to take the medicine safely. You should read this document thoroughly before starting your course. The PIL contains exhaustive lists of ingredients, potential interactions and updated safety guidance.
Lariam works by killing the malaria parasites once they enter the bloodstream, preventing them from multiplying within the red blood cells. By maintaining a consistent level of mefloquine in your system, the medication acts as a protective barrier that stops the infection from developing into a serious illness.
To ensure maximum protection, you should take Lariam exactly as directed by your healthcare provider. The tablets should be swallowed whole with plenty of water, preferably after a main meal to reduce the risk of stomach upset. Do not chew or suck the tablets.
The standard adult dosage for malaria prevention is one 250mg tablet taken once a week. You should start the course at least 10 days before you enter a malaria-risk area, continue weekly throughout your stay and keep taking it for 4 weeks after you return to the UK.
Like all medicines, Lariam can cause side effects, although not everyone gets them. While many people experience no issues, it is important to be aware of potential reactions.
- Common side effects: Nausea, dizziness, headache, and sleep disturbances (such as insomnia or vivid dreams).
- Neuropsychiatric effects: In rare cases, Lariam can cause anxiety, depression, or feelings of confusion.
- Gastrointestinal issues: Diarrhoea or abdominal pain may occur shortly after taking a dose.
Lariam is not suitable for everyone and must be prescribed with caution. You should inform your prescriber if you have a history of mental health conditions, including depression or anxiety, or if you suffer from epilepsy. It should not be taken alongside certain other medications, such as halofantrine, as this can affect heart rhythm.
When choosing an antimalarial, it is helpful to compare the different options available in the UK based on your destination and lifestyle.
| Feature | Lariam (Mefloquine) | Malarone (Atovaquone/Proguanil) | Doxycycline |
|---|---|---|---|
| Frequency | Once weekly | Once daily | Once daily |
| Start before travel | 1-3 weeks | 1-2 days | 1-2 days |
| Continue after travel | 4 weeks | 7 days | 4 weeks |
Can I drink alcohol while taking Lariam?
While there is no direct contraindication with alcohol, it is generally advised to limit consumption as both alcohol and Lariam can cause dizziness and affect your coordination.
Is Lariam safe for children?
Lariam can be used for children over 5kg in weight, but the dosage must be carefully calculated based on their body mass. Our clinical team can advise on suitability during the consultation.
What if I forget to take my weekly dose?
If you miss a dose, take it as soon as you remember and then continue your weekly schedule. Do not take a double dose to make up for a forgotten one.
The information provided on this page is for general informational purposes only and should not replace seeking advice from a medical professional for personalised advice. Always consult with a doctor or pharmacist before starting a new medication to ensure it is safe for your individual health needs.
Our content is regularly reviewed by our team of medical experts to ensure it is up to date and accurate, reflecting the latest clinical guidelines in the UK.

